Perioperative neurocognitive disorders (PND) commonly occur in elderly patients, and
isoflurane could be a risk factor. During the pathogenesis of neurodegeneration, the …

Methods: This retrospective study, after approval, was conducted in elective non-cardiac
surgery patients≥ 65 years old. We assessed the relationship between processing speed …

Isoflurane has been demonstrated to induce mitochondrial damage and cell apoptosis. The
isoflurane-induced inflammation may be an important reason for this phenomenon. Studies …

[摘要] 目的探讨利多卡因对血管内皮细胞粘附因子表达的影响. 方法采用不同浓度利多卡因预
处理脐带静脉内皮细胞(HUVECs) 30 min 后, 加入肿瘤坏死因子α (TNFα) 进行刺激 …

Postoperative cognitive dysfunction (POCD) is a cognitive impairment that develops early
and persists in the late postoperative period. Postoperative cognitive dysfunction refers to …

Thirty fluoro-substituted lidocaine analogs (10a–e, 11a–e, 14a–e, 15a–e, 18a–e and 19a–e)
were synthesized, and their sciatic nerve block activity were evaluated as local anesthesia …

Пациенты группы «высокого риска развития кардиальных осложнений» и «старое»
сердце―не одно и то же, но для анестезиолога―это звенья единой цепи …

Background: The use of isoflurane sedation for prolonged periods in the critical care
environment is increasing. However, isoflurane-mediated neurotoxicity has been widely …