Mechanism of bile acid-induced programmed cell death and drug discovery against cancer: A review
JY Jang, E Im, YH Choi, ND Kim - International Journal of Molecular …, 2022 - mdpi.com
Bile acids are major signaling molecules that play a significant role as emulsifiers in the
digestion and absorption of dietary lipids. Bile acids are amphiphilic molecules produced by …
digestion and absorption of dietary lipids. Bile acids are amphiphilic molecules produced by …
Roles and inhibitors of FAK in cancer: current advances and future directions
HH Hu, SQ Wang, HL Shang, HF Lv… - Frontiers in …, 2024 - frontiersin.org
Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that exhibits high expression
in various tumors and is associated with a poor prognosis. FAK activation promotes tumor …
in various tumors and is associated with a poor prognosis. FAK activation promotes tumor …
The characteristics and the multiple functions of integrin β1 in human cancers
L Sun, S Guo, Y Xie, Y Yao - Journal of Translational Medicine, 2023 - Springer
Integrins, which consist of two non-covalently linked α and β subunits, play a crucial role in
cell–cell adhesion and cell-extracellular matrix (ECM) interactions. Among them, integrin β1 …
cell–cell adhesion and cell-extracellular matrix (ECM) interactions. Among them, integrin β1 …
A predictive molecular signature consisting of lncRNAs associated with cellular senescence for the prognosis of lung adenocarcinoma
A Liu, X Wang, L Hu, D Yan, Y Yin, H Zheng, G Liu… - Plos one, 2023 - journals.plos.org
The role of long noncoding RNAs (lncRNAs) has been verified by more and more
researches in recent years. However, there are few reports on cellular senescence …
researches in recent years. However, there are few reports on cellular senescence …
Combating anoikis resistance: bioactive compounds transforming prostate cancer therapy
The study aims to discuss the challenges associated with treating prostate cancer (PCa),
which is known for its complexity and drug resistance. It attempts to find differentially …
which is known for its complexity and drug resistance. It attempts to find differentially …
Revealing a Novel Methylated Integrin Alpha-8 Related to Extracellular Matrix and Anoikis Resistance Using Proteomic Analysis in the Immune Microenvironment of …
T Liu, W Ji, X Cheng, L Lv, X Yu, N Wang, M Li… - Molecular …, 2024 - Springer
Genomic epigenetics of extracellular matrix (ECM) play an important role in lung
adenocarcinoma (LUAD). Our study identified a signature of potential prognostic genes …
adenocarcinoma (LUAD). Our study identified a signature of potential prognostic genes …
Development of a prognostic model for lung adenocarcinoma polarity‐related genes and analysis of immune landscape
H Xu, W Du, X Jing, J Xie, P Li - Biotechnology and Applied …, 2024 - Wiley Online Library
Despite the progress made in the management of lung adenocarcinoma (LUAD), the overall
prognosis for LUAD individuals remains suboptimal. While the role of cell polarity in tumor …
prognosis for LUAD individuals remains suboptimal. While the role of cell polarity in tumor …
Mode of actions of bile acids in avoidance of colorectal cancer development; and their therapeutic applications in cancers-a narrative review
KK Kaur, GNK Allahbadia, M Singh - Journal of Pharmacy and …, 2022 - set-publisher.com
Abstract Bile Acids (BAs) possess a considerably significant part in the form of emulsifiers in
digestion besides absorption of dietary lipids. BAs represent amphiphilic molecules, that are …
digestion besides absorption of dietary lipids. BAs represent amphiphilic molecules, that are …
Construction of a Prognostic Model for Lung Adenocarcinoma Based on Nucleotide Metabolism-Related Genes and Bioinformatics Analysis
X Cui, W Han, Y Li, R Zhang, G Zhu, H Huang, J Chen - 2024 - researchsquare.com
Background: Metabolic reprogramming is an important hallmark of cancer. However, it is still
uncertain how nucleotide metabolism-related genes (NMRGs) may affect the prognosis of …
uncertain how nucleotide metabolism-related genes (NMRGs) may affect the prognosis of …