Clostridioides difficile is the most common cause of nosocomial antibiotic-associated
diarrhea, and is responsible for a spectrum of diseases characterized by high levels of …

The pathogenic Clostridioides difficile and Clostridium perfringens are responsible for many
health care-associated infections as well as systemic and enteric diseases. Therefore, they …

C. difficile is a major cause of antibiotic-associated gastrointestinal infections. Two C. difficile
exotoxins (TcdA and TcdB) are major virulence factors associated with these infections, and …

Clostridioides difficile is one of the most common causes of antibiotic-associated diarrhea in
developed countries. As key virulence factors of C. difficile, toxin A (TcdA) and toxin B (TcdB) …

Clostridioides difficile is a global public health problem, which is a primary cause of
antibiotic-associated diarrhea in humans. The emergence of hypervirulent and antibiotic …

This review aims to provide a comprehensive overview of the significant Clostridioides
difficile molecular typing techniques currently employed in research and medical …

Clostridioides difficile, which causes life-threatening diarrheal disease, presents an urgent
threat to health care systems. In this study, we present a retrospective genomic and …

Toxin B (TcdB) is a primary cause of Clostridioides difficile infection (CDI). This toxin acts by
glucosylating small GTPases in the Rho/Ras families, but the structural basis for TcdB …

Clostridioides difficile is classified as an urgent antibiotic resistance threat by the Centers for
Disease Control and Prevention (CDC). C. difficile infection (CDI) is mainly caused by the C …

The Coronavirus disease 2019 (COVID-19) pandemic has brought new challenges across
medical disciplines, particularly in infectious disease medicine. In Romania, the incidence of …