Advances in mesenchymal stem cell transplantation for the treatment of osteoporosis

Y Jiang, P Zhang, X Zhang, L Lv, Y Zhou - Cell proliferation, 2021 - Wiley Online Library
Osteoporosis is a systemic metabolic bone disease with characteristics of bone loss and
microstructural degeneration. The personal and societal costs of osteoporosis are …

[HTML][HTML] Adipose-derived stem cells: Sources, potency, and implications for regenerative therapies

Z Si, X Wang, C Sun, Y Kang, J Xu, X Wang… - Biomedicine & …, 2019 - Elsevier
Adipose-derived stem cells (ASCs) are a subset of mesenchymal stem cells (MSCs) that can
be obtained easily from adipose tissues and possess many of the same regenerative …

[HTML][HTML] Distinct biological ages of organs and systems identified from a multi-omics study

C Nie, Y Li, R Li, Y Yan, D Zhang, T Li, Z Li, Y Sun… - Cell reports, 2022 - cell.com
Biological age (BA) has been proposed to evaluate the aging status instead of chronological
age (CA). Our study shows evidence that there might be multiple" clocks" within the whole …

[HTML][HTML] Advances and challenges in stem cell culture

C McKee, GR Chaudhry - Colloids and surfaces B: Biointerfaces, 2017 - Elsevier
Stem cells (SCs) hold great promise for cell therapy, tissue engineering, and regenerative
medicine as well as pharmaceutical and biotechnological applications. They have the …

Targeted therapy for inflammatory diseases with mesenchymal stem cells and their derived exosomes: from basic to clinics

S Wang, B Lei, E Zhang, P Gong, J Gu… - International Journal …, 2022 - Taylor & Francis
Inflammation is a beneficial and physiological process, but there are a number of
inflammatory diseases which have detrimental effects on the body. In addition, the drugs …

[HTML][HTML] The role of microRNAs in the osteogenic and chondrogenic differentiation of mesenchymal stem cells and bone pathologies

MR Iaquinta, C Lanzillotti, C Mazziotta, I Bononi… - Theranostics, 2021 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) have been identified in many adult tissues. MSCs can
regenerate through cell division or differentiate into adipocytes, osteoblasts and …

Self‐healing silk fibroin‐based hydrogel for bone regeneration: dynamic metal‐ligand self‐assembly approach

L Shi, F Wang, W Zhu, Z Xu, S Fuchs… - Advanced Functional …, 2017 - Wiley Online Library
Despite advances in the development of silk fibroin (SF)‐based hydrogels, current methods
for SF gelation show significant limitations such as lack of reversible crosslinking, use of …

Senile osteoporosis: the involvement of differentiation and senescence of bone marrow stromal cells

A Qadir, S Liang, Z Wu, Z Chen, L Hu… - International journal of …, 2020 - mdpi.com
Senile osteoporosis has become a worldwide bone disease with the aging of the world
population. It increases the risk of bone fracture and seriously affects human health. Unlike …

The relationship between bone marrow adipose tissue and bone metabolism in postmenopausal osteoporosis

J Li, X Chen, L Lu, X Yu - Cytokine & growth factor reviews, 2020 - Elsevier
Postmenopausal osteoporosis (PMOP) is a prevalent skeletal disorder associated with
menopause-related estrogen withdrawal. PMOP is characterized by low bone mass …

Carcinoma-associated mesenchymal stem/stromal cells: architects of the pro-tumorigenic tumor microenvironment

L Frisbie, RJ Buckanovich, L Coffman - Stem Cells, 2022 - academic.oup.com
The interaction between tumor cells and non-malignant hosts cells within the tumor
microenvironment (TME) is critical to the pathophysiology of cancer. These non-malignant …