International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors
BB Fredholm, AP IJzerman, KA Jacobson… - Pharmacological …, 2001 - ASPET
Four adenosine receptors have been cloned and characterized from several mammalian
species. The receptors are named adenosine A1, A2A, A2B, and A3. The A2A and A2B …
species. The receptors are named adenosine A1, A2A, A2B, and A3. The A2A and A2B …
The pharmacology and clinical pharmacology of 3, 4-methylenedioxymethamphetamine (MDMA,“ecstasy”)
AR Green, AO Mechan, JM Elliott, E O'Shea… - Pharmacological …, 2003 - ASPET
The amphetamine derivative (±)-3, 4-methylenedioxymethamphetamine (MDMA, ecstasy) is
a popular recreational drug among young people, particularly those involved in the dance …
a popular recreational drug among young people, particularly those involved in the dance …
Adenosine and brain function
BB Fredholm, JF Chen, RA Cunha… - Int Rev …, 2005 - books.google.com
A. Cellular and Subcellular Localization B. Pharmacological Tools to Study Adenosine
Receptors C. Signaling Via Adenosine Receptors D. Regulation of Receptor Expression and …
Receptors C. Signaling Via Adenosine Receptors D. Regulation of Receptor Expression and …
Caffeine as a psychomotor stimulant: mechanism of action
The popularity of caffeine as a psychoactive drug is due to its stimulant properties, which
depend on its ability to reduce adenosine transmission in the brain. Adenosine A 1 and A 2A …
depend on its ability to reduce adenosine transmission in the brain. Adenosine A 1 and A 2A …
Dopaminergic role in stimulant-induced wakefulness
JP Wisor, S Nishino, I Sora, GH Uhl… - Journal of …, 2001 - Soc Neuroscience
The role of dopamine in sleep regulation and in mediating the effects of wake-promoting
therapeutics is controversial. In this study, polygraphic recordings and caudate …
therapeutics is controversial. In this study, polygraphic recordings and caudate …
Genetics of caffeine consumption and responses to caffeine
Rationale Caffeine is widely consumed in foods and beverages and is also used for a
variety of medical purposes. Despite its widespread use, relatively little is understood …
variety of medical purposes. Despite its widespread use, relatively little is understood …
[HTML][HTML] Association between ADORA2A and DRD2 polymorphisms and caffeine-induced anxiety
E Childs, C Hohoff, J Deckert, K Xu, J Badner… - …, 2008 - nature.com
Caffeine produces mild psychostimulant and sometimes anxiogenic effects by antagonizing
adenosine at A 1 and A 2A receptors, and perhaps through interactions with other …
adenosine at A 1 and A 2A receptors, and perhaps through interactions with other …
Actions of adenosine at its receptors in the CNS: insights from knockouts and drugs
BB Fredholm, JF Chen, SA Masino… - Annu. Rev. Pharmacol …, 2005 - annualreviews.org
▪ Abstract Adenosine and its receptors have been the topic of many recent reviews (–).
These reviews provide a good summary of much of the relevant literature—including the …
These reviews provide a good summary of much of the relevant literature—including the …
Molecular mechanisms and therapeutical implications of intramembrane receptor/receptor interactions among heptahelical receptors with examples from the …
The molecular basis for the known intramembrane receptor/receptor interactions among G
protein-coupled receptors was postulated to be heteromerization based on receptor subtype …
protein-coupled receptors was postulated to be heteromerization based on receptor subtype …
The role of the D2 dopamine receptor (D2R) in A2A adenosine receptor (A2AR)-mediated behavioral and cellular responses as revealed by A2A and D2 …
JF Chen, R Moratalla, F Impagnatiello… - Proceedings of the …, 2001 - National Acad Sciences
The A2AR is largely coexpressed with D2Rs and enkephalin mRNA in the striatum where it
modulates dopaminergic activity. Activation of the A2AR antagonizes D2R-mediated …
modulates dopaminergic activity. Activation of the A2AR antagonizes D2R-mediated …