Gene knockout approach to adenosine A2A receptors in Parkinson's disease

JF Chen, MA Schwarzschild - Drug development research, 2003 - Wiley Online Library
Recently, the adenosine A2A receptor (A2AR) has emerged as an attractive target for
Parkinson's disease (PD) treatment by virtue of its coexpression with the dopamine D2 …

[HTML][HTML] Atividade da Metilxantina em pó aplicada na cama de frango sobre adultos de Alphitobius diaperinus (Panzer, 1797) (Coleoptera: Tenebrionidae)

MM Ishizuka, NSM Leandro, JMS Silva… - Ciência Animal …, 2022 - SciELO Brasil
Uma das pragas que mais afetam e comprometem a produção avícola no mundo é o inseto
Alphitobius diaperinus, conhecido como cascudinho. Este inseto é vetor de doenças que …

[PDF][PDF] Adenosine receptor modulation of GABAergic transmission

AM Sebastião, DM Rombo… - Adenosine Signal. Mech …, 2015 - novapublishers.com
Neurotransmission mediated by γ-aminobutyric acid (GABA) is well established, as GABA is
the predominant inhibitory transmitter in the adult brain. The multiplicity of inhibitory neurons …

[HTML][HTML] Adenosine A2A Receptor Gene Knockout Prevents l-3,4-Dihydroxyphenylalanine-Induced Dyskinesia by Downregulation of Striatal GAD67 in 6-OHDA …

S Yin, X Zhang, S Chen, W Yang, X Zheng… - Frontiers in …, 2017 - frontiersin.org
l-3, 4-Dihydroxyphenylalanine (l-DOPA) remains the primary pharmacological agent for the
symptomatic treatment of Parkinson's disease (PD). However, the development of l-DOPA …

Using caffeine for physical exercise: advantages and risks

CA Ramírez-Montes, JH Osorio - Revista de la Facultad de Medicina, 2013 - scielo.org.co
Objetivo. El presente artículo de revisión tiene como objetivo analizar la información
científica disponible y actualizar al lector con relación al uso de la cafeína como sustancia …

Distinctive and Synergistic Signaling of Human Adenosine A2a and Dopamine D2L Receptors in CHO Cells

Y Tang, KT Demarest - Journal of Receptors and Signal …, 2005 - Taylor & Francis
Adenosine A2 a receptor (A2 a R) colocalizes with dopamine D2 receptor (D2R) in the basal
ganglia and modulates D2R-mediated dopaminergic activities. A2 a R and D2R couple to …

The effects of dexamphetamine, nabilone (a synthetic cannabinoid agonist), and caffeine on working memory, schizotypy and a tactile illusion in healthy volunteers

FM Kassim - 2021 - research-repository.uwa.edu.au
The thesis aimed to examine the effects of dopamine-releasing agents and cannabinoids on
working memory (WM), schizotypy and stimulus binding windows (BWs) by manipulating …

[图书][B] Caffeine modulation of ethanol: Effects on intake, metabolism, and adenosine receptor-mediated dopamine neurotransmission in the medial prefrontal cortex of …

KM Franklin - 2009 - search.proquest.com
The consumption of caffeinated alcoholic beverages has shown increased prevalence in
recent years. Research suggests that combining these drugs may lead to different effects …

[图书][B] Molecular and functional interactions between adenosine and dopamine receptors. New therapeutic targets for the treatment of Parkinson's disease.

M Canals Buj - 2004 - diposit.ub.edu
Adenosine and dopamine receptors are members of the GPCRs family for which a
significant segregation between their A2A and D2 subtypes has been demonstrated in the …

[PDF][PDF] Adenosine A2A receptor antagonist treatment of Parkinson's disease

A Pinna, N Simola, M Morelli - 2007 - um.edu.mt
Adenosine A2A receptors have a unique cellular and regional distribution in the basal
ganglia (BG), being particularly concentrated in areas richly innervated by dopamine (DA) …