Inflammation is a complex biological defense system associated with a series of chronic
diseases such as cancer, arthritis, diabetes, cardiovascular and neurodegenerative …

Rheumatoid arthritis (RA) is an autoimmune disease involving joints, with clinical
manifestations of joint inflammation, bone damage and cartilage destruction, joint …

Rheumatoid arthritis (RA) is a type of chronic autoimmune and inflammatory disease. In the
pathological process of RA, the alteration of fibroblast-like synoviocyte (FLS) and its related …

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) helicase NSP13 plays
a conserved role in the replication of coronaviruses and has been identified as an ideal …

Plants rich in hydrolyzable tannins were traditionally used all over the world for a variety of
chronic inflammatory disorders, including arthritis, colitis, and dermatitis. However, the …

Purpose Neurodegenerative diseases are associated with neuroinflammation along with
activation of microglia and oxidative stress, but currently lack effective treatments …

Inflammation is the primary response to infection and injury. Its beneficial effect is an
immediate resolution of the pathophysiological event. However, sustained production of …

Psoriasis is a chronic and inflammatory skin disorder characterized by inflammation and
epidermal hyperplasia. Punicalagin (PUN) is a main active ingredient of pomegranate …

Ethnopharmacological relevance Pomegranate'Punica granatum'offers multiple health
benefits, including managing hypertension, dyslipidemia, hyperglycemia, insulin resistance …

As one of the key bioactive food ingredients in pomegranate, punicalagin (PA) possesses
wide-ranging functional activities. However, the knowledge on PA-modulated microbial …