Advances in the discovery of genetic elements underlying longissimus dorsi muscle growth and development in the pig

Q Zeng, ZQ Du - Animal Genetics, 2023 - Wiley Online Library
As a major source of protein in human diets, pig meat plays a crucial role in ensuring global
food security. Key determinants of meat production refer to the chemical and physical …

Molecular quantitative trait loci in reproductive tissues impact male fertility in cattle

XM Mapel, NK Kadri, AS Leonard, Q He… - nature …, 2024 - nature.com
Breeding bulls are well suited to investigate inherited variation in male fertility because they
are genotyped and their reproductive success is monitored through semen analyses and …

PigBiobank: a valuable resource for understanding genetic and biological mechanisms of diverse complex traits in pigs

H Zeng, W Zhang, Q Lin, Y Gao, J Teng… - Nucleic acids …, 2024 - academic.oup.com
To fully unlock the potential of pigs as both agricultural species for animal-based protein
food and biomedical models for human biology and disease, a comprehensive …

Recent advances in the genomic resources for sheep

SA Woolley, M Salavati, EL Clark - Mammalian Genome, 2023 - Springer
Sheep (Ovis aries) provide a vital source of protein and fibre to human populations. In
coming decades, as the pressures associated with rapidly changing climates increase …

Multi-omic characterization of allele-specific regulatory variation in hybrid pigs

J Quan, M Yang, X Wang, G Cai, R Ding… - Nature …, 2024 - nature.com
Hybrid mapping is a powerful approach to efficiently identify and characterize genes
regulated through mechanisms in cis. In this study, using reciprocal crosses of the …

Introgression of pigs in Taihu Lake region possibly contributed to the improvement of fertility in Danish Large White pigs

C Liu, R Huang, G Su, L Hou, W Zhou, Q Liu, Z Qiu… - BMC genomics, 2023 - Springer
Background Eurasian pigs have undergone lineage admixture throughout history. It has
been confirmed that the genes of indigenous pig breeds in China have been introduced into …

[HTML][HTML] Characterizing structural variants based on graph-genotyping provides insights into pig domestication and local adaption

X Li, Q Liu, C Fu, M Li, C Li, X Li, S Zhao… - Journal of Genetics and …, 2024 - Elsevier
Structural variants (SVs), such as deletions (DELs) and insertions (INSs), contribute
substantially to pig genetic diversity and phenotypic variation. Using a library of SVs …

FarmGTEx TWAS-server: an interactive web server for customized TWAS analysis in both human and farm animals

Z Zhang, Z Chen, J Teng, S Liu, Q Lin, Y Gao, Z Bai… - bioRxiv, 2023 - biorxiv.org
Transcriptome-wide association study (TWAS) is a powerful strategy for elucidating the
molecular mechanisms behind the genetic loci of complex phenotypes. However, TWAS …

Comprehensive Analysis of CircRNA Expression Profiles in Multiple Tissues of Pigs

Q Shen, W Gong, X Pan, J Cai, Y Jiang, M He… - International journal of …, 2023 - mdpi.com
Circular RNAs (circRNAs) are a class of non-coding RNAs with diverse functions, and
previous studies have reported that circRNAs are involved in the growth and development of …

Genetic diversity, tissue-specific expression, and functional analysis of the ATP7A gene in sheep

H Li, X Du, X Li, P Feng, M Chu, Y Jin, Z Pan - Frontiers in Genetics, 2023 - frontiersin.org
In humans, variation of the ATP7A gene may cause cranial exostosis, which is similar to
“human horn,” but the function of the ATP7A gene in sheep is still unknown. Tissue …