The muscle extracellular matrix (ECM) forms a complex network of collagens, proteoglycans,
and other proteins that produce a favorable environment for muscle regeneration, protect the …

Resveratrol is a natural polyphenol utilized in Chinese traditional medicine and thought to
be one of the determinants of the “French Paradox”. More recently, some groups evidenced …

Background Skeletal muscle atrophy in chronic kidney disease (CKD) leads to a decline in
quality of life and increased risk of morbidity and mortality. We have obtained evidence that …

Significance: An estimated 700 million people globally suffer from chronic kidney disease
(CKD). In addition to increasing cardiovascular disease risk, CKD is a catabolic disease that …

Background: Anterior cruciate ligament (ACL) tear (ACLT) leads to protracted quadriceps
muscle atrophy. Protein turnover largely dictates muscle size and is highly responsive to …

Musculoskeletal disorders contribute substantially to worldwide disability. Anterior cruciate
ligament (ACL) tears result in unresolved muscle weakness and posttraumatic osteoarthritis …

Abstract Purpose of Review To provide an overview of the recent literature investigating the
pathophysiology of skeletal muscle changes, interventions for skeletal muscle, and effects of …

Frailty is a condition that is frequently observed among patients undergoing dialysis. Frailty
is characterized by a decline in both physiological state and cognitive state, leading to a …

Rationale & Objective Previous studies in chronic kidney disease (CKD) showed that
vascular dysfunction in different circulatory beds progressively deteriorates with worsening …

Metabolic acidosis is common in people with chronic kidney disease and can contribute to
functional decline, morbidity, and mortality. One avenue through which metabolic acidosis …