Human prostate cancer risk factors

DG Bostwick, HB Burke, D Djakiew… - … Journal of the …, 2004 - Wiley Online Library
Prostate cancer has the highest prevalence of any nonskin cancer in the human body, with
similar likelihood of neoplastic foci found within the prostates of men around the world …

Soy isoflavones and prostate cancer: a review of molecular mechanisms

AM Mahmoud, W Yang, MC Bosland - The Journal of steroid biochemistry …, 2014 - Elsevier
Soy isoflavones are dietary components for which an association has been demonstrated
with reduced risk of prostate cancer (PCa) in Asian populations. However, the exact …

Maternal Genistein Alters Coat Color and Protects Avy Mouse Offspring from Obesity by Modifying the Fetal Epigenome

DC Dolinoy, JR Weidman… - Environmental health …, 2006 - ehp.niehs.nih.gov
Genistein, the major phytoestrogen in soy, is linked to diminished female reproductive
performance and to cancer chemoprevention and decreased adipose deposition. Dietary …

Soy isoflavones and cancer prevention: clinical science review

FH Sarkar, Y Li - Cancer investigation, 2003 - Taylor & Francis
Epidemiological studies have shown a significant difference in cancer incidence among
different ethnic groups, which is believed to be partly attributed to dietary habits. The …

Phytoestrogens derived from red clover: an alternative to estrogen replacement therapy?

V Beck, U Rohr, A Jungbauer - The Journal of steroid biochemistry and …, 2005 - Elsevier
The benefits of plant extracts from soy and red clover as alternatives to conventional
hormone replacement therapy (HRT) have been debated in the past. Here, an attempt has …

Phyto-oestrogens, their mechanism of action: current evidence for a role in breast and prostate cancer

PJ Magee, IR Rowland - British Journal of Nutrition, 2004 - cambridge.org
The incidence of hormone-dependent cancers, such as those of the breast and prostate, is
much lower in Eastern countries such as China and Japan in comparison with the Western …

Combinatorial epigenetic mechanisms of sulforaphane, genistein and sodium butyrate in breast cancer inhibition

M Sharma, TO Tollefsbol - Experimental Cell Research, 2022 - Elsevier
Dietary phytochemicals are currently being studied with great interest due to their ability to
regulate the epigenome resulting in prevention of cancer. Some natural botanicals have …

Cellular signaling perturbation by natural products

FH Sarkar, Y Li, Z Wang, D Kong - Cellular signalling, 2009 - Elsevier
Cancer cells are known to have alterations in multiple cellular signaling pathways and
because of the complexities in the communication between multiple signaling networks, the …

Phytoestrogen supplements for the treatment of hot flashes: the Isoflavone Clover Extract (ICE) Study: a randomized controlled trial

JA Tice, B Ettinger, K Ensrud, R Wallace, T Blackwell… - Jama, 2003 - jamanetwork.com
ContextClinical trials demonstrating increased risk of cardiovascular disease and breast
cancer among women randomized to hormone replacement therapy have increased interest …

The effects of soy isoflavones on obesity

A Ørgaard, L Jensen - Experimental Biology and Medicine, 2008 - journals.sagepub.com
Over the last decades, the prevalence of obesity and related diseases has increased rapidly
in the Western world. Obesity is a disorder of energy balance and is associated with hyper …