Over the last decades, the prevalence of obesity and related diseases has increased rapidly
in the Western world. Obesity is a disorder of energy balance and is associated with hyper …

Background: Dietary modifications to prevent prostate cancer (PCa) continue to gain
attention as research demonstrates that various dietary nutrients/supplements are related to …

A high intake of fruits and vegetables is associated with a lower risk of cancer. In this context,
considerable attention is paid to Asian populations who consume high amounts of soy and …

Breast and prostate cancers are among the most common of all cancers. They are referred
to as hormone‐dependent cancers, because estrogen and androgen are involved in their …

CONTEXT: Oestrogens were proven effective in the hormonal treatment of advanced
prostate cancer (PCa)> 60 yr ago and are still used as second-line hormonal therapy …

Hormone-refractory relapse is an inevitable and lethal event for advanced prostate cancer
patients after hormone deprivation. A growing body of evidence indicates that hormone …

Phyto-oestrogens are oestrogenic compounds found in plants and consist of isoflavones,
lignans and coumestans. Epidemiological studies provide evidence for a protective role of …

Background Estrogen receptor-α (ERα)-negative breast cancer is clinically aggressive and
normally does not respond to conventional estrogen target-directed therapies. The soybean …

Dietary compounds that possess the properties of altering epigenetic processes are gaining
popularity as targets for cancer prevention studies. These compounds when administered at …

Soy isoflavones, the focus of much research and controversy, are often referred to as “weak
estrogens”. In fact, genistein is a relatively potent agonist for the recently characterized beta …