Genistein, one of the predominant soy isoflavones, has been shown to compete with 17 β-
estradiol for estrogen receptor binding because of its structural similarity, resulting in …

Epidemiological studies have indicated a significant difference in the incidence of cancers
among ethnic groups, who have different lifestyles and have been exposed to different …

Glucocorticoids and estrogens regulate a number of vital physiological processes. We
developed a model breast cancer cell line, MCF-7 M, to examine potential mechanisms by …

The role of epigenetic alterations in various human chronic diseases has gained increasing
attention and has resulted in a paradigm shift in our understanding of disease susceptibility …

The aberrant behavior of cancer reflects upregulation of certain oncogenic signaling
pathways that promote proliferation, inhibit apoptosis, and enable the cancer to spread and …

Dietary habits and incidence of prostate cancer (PCa) are very different in several parts of
the world. Among the differences between Eastern and Western diets is the greater intake of …

Scope Reduced expression of tumor suppressor genes (TSG) increases the susceptibility to
breast cancer. However, only a small percentage of breast tumors is related to family history …

Cancer cells exhibit deregulation in multiple cellular signaling pathways. Therefore,
treatments using specific agents that target only one pathway usually fail in cancer therapy …

Objective Based on evidence that phytoestrogens may protect against prostate cancer, we
evaluated the associations between serum enterolactone concentration or dietary …

OBJECTIVES: To determine the effects of diets rich in soy and linseed compared with a
control diet on biochemical markers of prostate cancer in men diagnosed with prostate …