[HTML][HTML] Epigenetic regulation of multiple tumor-related genes leads to suppression of breast tumorigenesis by dietary genistein

Y Li, H Chen, TM Hardy, TO Tollefsbol - PloS one, 2013 - journals.plos.org
Breast cancer is one of the most lethal diseases in women; however, the precise etiological
factors are still not clear. Genistein (GE), a natural isoflavone found in soybean products, is …

[HTML][HTML] Molecular mechanisms and bioavailability of polyphenols in prostate cancer

T Costea, P Nagy, C Ganea, J Szöllősi… - International journal of …, 2019 - mdpi.com
Prostate cancer is the one of the most frequently diagnosed cancers among men over the
age of 50. Several lines of evidence support the observation that polyphenols have …

Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function

S Basak, D Pookot, EJ Noonan, R Dahiya - Molecular cancer therapeutics, 2008 - AACR
Androgen receptor (AR) is a ligand-activated transcription factor belonging to the steroid
hormone receptor family and is very important for the development and progression of …

Induction of apoptosis in low to moderate-grade human prostate carcinoma by red clover-derived dietary isoflavones

RA Jarred, M Keikha, C Dowling, SJ McPherson… - … Biomarkers & Prevention, 2002 - AACR
Epidemiological evidence suggests a geographical basis for the incidence of prostate
cancer and dietary factors, including isoflavone consumption, may be linked to this …

Emerging evidence on the role of soy in reducing prostate cancer risk

MJ Messina - Nutrition reviews, 2003 - academic.oup.com
Soyfoods are a unique dietary source of isoflavones, which have both hormonal and non-
hormonal effects relevant to prostate cancer prevention. In vitro, the main soybean …

[HTML][HTML] Androgen receptor and soy isoflavones in prostate cancer

MK Sivoňová, P Kaplán… - Molecular and …, 2019 - spandidos-publications.com
Androgens and androgen receptor (AR) play a critical role not only in normal prostate
development, but also in prostate cancer. For that reason, androgen deprivation therapy …

Daidzein: bioavailability, potential for reproductive toxicity, and breast cancer chemoprevention in female rats

CA Lamartiniere, J Wang… - Toxicological …, 2002 - academic.oup.com
Soy products containing phytoestrogens have received much attention as dietary
components to promote better health. Daidzein, an isoflavone and phytoestrogen …

Lesson learned from nature for the development of novel anti-cancer agents: implication of isoflavone, curcumin, and their synthetic analogs

FH Sarkar, Y Li, Z Wang… - Current pharmaceutical …, 2010 - ingentaconnect.com
In recent years, naturally occurring dietary compounds have received greater attention in the
field of cancer prevention and treatment research. Among them, isoflavone genistein and …

[HTML][HTML] Impact of physical exercise on growth and progression of cancer in rodents—a systematic review and meta-analysis

RCKR Eschke, A Lampit, A Schenk, F Javelle… - Frontiers in …, 2019 - frontiersin.org
Background: Physical exercise is suspected to reduce cancer risk and mortality. So far, little
is known about the underlying mechanisms. Although limited, murine models represent a …

Phytoestrogens in common herbs regulate prostate cancer cell growth in vitro

NS Shenouda, C Zhou, JD Browning, PJ Ansell… - Nutrition and …, 2004 - Taylor & Francis
Prostate cancer is an important public health problem in the United States. Seven
phytoestrogens found in common herbal products were screened for estrogen receptor …