[HTML][HTML] The use of soy isoflavones in the treatment of prostate cancer: a focus on the cellular effects

H Van der Eecken, S Joniau, C Berghen, K Rans… - Nutrients, 2023 - mdpi.com
A possible link between diet and cancer has long been considered, with growing interest in
phytochemicals. Soy isoflavones have been associated with a reduced risk of prostate …

Androgen receptor regulation by physiological concentrations of the isoflavonoid genistein in androgen-dependent LNCaP cells is mediated by estrogen receptor β

J Bektic, AP Berger, K Pfeil, G Dobler, G Bartsch… - European urology, 2004 - Elsevier
Objectives: Isoflavonoids are discussed for use in chemoprevention and treatment of
prostate cancer. We investigated the potential of genistein to modulate androgen receptor …

Exposure to phytoestrogens in the perinatal period affects androgen secretion by testicular Leydig cells in the adult rat

BT Akingbemi, TD Braden, BW Kemppainen… - …, 2007 - academic.oup.com
The use of soy-based products in the diet of infants has raised concerns regarding the
reproductive toxicity of genistein and daidzein, the predominant isoflavones in soybeans …

Dietary genistein suppresses chemically induced prostate cancer in Lobund–Wistar rats

J Wang, IE Eltoum, CA Lamartiniere - Cancer letters, 2002 - Elsevier
Epidemiological reports suggest that Asians consuming a diet high in soy have a low
incidence of clinically manifested prostate cancer. We have tested the hypothesis that life …

[HTML][HTML] Acute exposure of adult male rats to dietary phytoestrogens reduces fecundity and alters epididymal steroid hormone receptor expression

A Glover, SJ Assinder - Journal of endocrinology, 2006 - joe.bioscientifica.com
Phytoestrogens are plant-derived compounds with oestrogenic activity. They are common in
both human and animal diets, particularly through soy-based foods. This study assessed …

[HTML][HTML] Adult-only exposure of male rats to a diet of high phytoestrogen content increases apoptosis of meiotic and post-meiotic germ cells

S Assinder, R Davis, M Fenwick, A Glover - Reproduction, 2007 - rep.bioscientifica.com
Apoptosis plays a critical role in regulating sperm production. Removal of androgens and
gonadotropins, or estrogen administration induces germ cell apoptosis. It is hypothesized …

Is daidzein non-metabolizer a high risk for prostate cancer? A case-controlled study of serum soybean isoflavone concentration

H Akaza, N Miyanaga, N Takashima… - Japanese Journal of …, 2002 - academic.oup.com
Background: It has been postulated that soybean isoflavones act as inhibitory factors in
prostate cancer. However, to date there have been no case-controlled clinical studies …

Isoflavones and the prevention of breast and prostate cancer: new perspectives opened by nutrigenomics

C Steiner, S Arnould, A Scalbert… - British Journal of Nutrition, 2008 - cambridge.org
Epidemiological evidence together with preclinical data from animal and in vitro studies
strongly support a correlation between soy isoflavone consumption and protection towards …

Inhibition of core histone acetylation by the cancer preventive peptide lunasin

HJ Jeong, JB Jeong, DS Kim… - Journal of agricultural …, 2007 - ACS Publications
Lunasin is a unique 43 amino acid soy peptide that has been shown to be chemopreventive
in mammalian cells and in a skin cancer mouse model in this work against oncogenes and …

Effects of plant polyphenols on ovarian follicular reserve in aging rats

ZG Chen, LL Luo, JJ Xu, XL Zhuang… - … and Cell Biology, 2010 - cdnsciencepub.com
The pool of ovarian primordial follicles is established during embryonic development or at
birth. During the development from primordial to primary, secondary, and antral follicles, only …