Asthma is a complex and heterogeneous chronic inflammatory disease of the airways.
Alongside environmental factors, asthma susceptibility is strongly influenced by genetics …

Prosperous advances in understanding the cellular and molecular mechanisms of chronic
inflammation and airway remodeling in asthma have been made over the past several …

Asthma represents a chronic respiratory disease affecting millions of children worldwide.
The transition from preschool wheezing to school‐age asthma involves a multifaceted …

Background So far, quite a few studies have revealed that systemic iron levels are related to
asthmatic inflammatory reactions. And most studies have focused on the correlation …

Abstract Introduction Type 2 (T2) inflammation is a key mechanism in the pathophysiology of
asthma. Diet may have immunomodulatory effects, and a role for diet in T2 inflammation has …

Background Although clinical features of type 2 inflammation have been associated with
poorer longitudinal outcomes in preschool children with recurrent wheezing, it remains …

We investigated the stability of T2 low status, based on low levels of T2 biomarkers, and
exacerbation rates in T2 low and non-T2 low asthma from clinical retrospective data of …

Introduction Wheezing disorders in preschool children are common. Current treatment
approaches assume all preschool wheezers are the same and will respond to a short course …

Childhood asthma is a chronic heterogeneous syndrome consisting of different disease
entities or phenotypes. The immunologic and cellular processes that occur during asthma …

In the 1980s many industrialized countries experienced large increases in the prevalence of
asthma with the term 'asthma epidemic'becoming popular. 1, 2 Since epidemiology had …