Autophagy is an intracellular catabolic self-cannibalism that eliminates dysfunctional
cytoplasmic cargos by the fusion of cargo-containing autophagosomes with lysosomes to …

Currently, the number of new cancer cases and deaths worldwide is increasing year on
year. In addition to the requirement for cancer prevention, the top priority is still to seek the …

Hydrolysis of glucobrassicin by plant or bacterial myrosinase produces multiple indoles
predominantly indole-3-carbinol (I3C). I3C and its major in vivo product, 3, 3' …

Aims Recently, chemoresistance has been recognized as an obstacle in the treatment of
gastric cancer (GC). The aim of this study was to investigate the biological functions and …

Gallbladder carcinoma (GBC), the most common malignant tumour of the bile duct, is highly
aggressive and has a poor prognosis. MicroRNA-30a-5p (miR-30a-5p) is an important …

Indole alkaloids, which are abundant in nature, are a significant source of pharmacologically
active compounds. Indole alkaloids have the potential to exert anticancer activity via various …

Cancer is the manifestation of changes and mutations in genetic and epigenetic levels. Non-
coding RNAs (ncRNAs) are commonly dysregulated in disease pathogenesis, and their role …

The positive results of the apatinib phase III trial have cast new light on treatment for patients
with advanced gastric cancer (GC). However, in terms of safety, apatinib toxicities may lead …

Gastric cancer is the fifth most common cancer, and the third most prevalent cause of cancer-
related deaths in the world. Voluminous evidence has demonstrated that phytochemicals …

Epigenetic alterations, such as DNA methylation, histone modifications and miRNAs, have a
significant role play in malignant cellular transformation and metastasis. On the other hand …