The glymphatic system: a novel component of fundamental neurobiology

LM Hablitz, M Nedergaard - Journal of Neuroscience, 2021 - Soc Neuroscience
Throughout the body, lymphatic fluid movement supports critical functions including
clearance of excess fluid and metabolic waste. The glymphatic system is the analog of the …

The human connectome in Alzheimer disease—relationship to biomarkers and genetics

M Yu, O Sporns, AJ Saykin - Nature Reviews Neurology, 2021 - nature.com
The pathology of Alzheimer disease (AD) damages structural and functional brain networks,
resulting in cognitive impairment. The results of recent connectomics studies have now …

[HTML][HTML] The role of gamma oscillations in central nervous system diseases: Mechanism and treatment

A Guan, S Wang, A Huang, C Qiu, Y Li, X Li… - Frontiers in cellular …, 2022 - frontiersin.org
Neural oscillations are rhythmic electric activities of neuron groups in the brain, and gamma
oscillation is the synchronization with a frequency of 30-90 Hz. The generation of gamma …

Toward noninvasive brain stimulation 2.0 in Alzheimer's disease

A Menardi, S Rossi, G Koch, H Hampel… - Ageing research …, 2022 - Elsevier
Noninvasive brain stimulation techniques (NiBS) have gathered substantial interest in the
study of dementia, considered their possible role in help defining diagnostic biomarkers of …

Spatially resolved neural slowing predicts impairment and amyloid burden in Alzheimer's disease

AI Wiesman, DL Murman, RA Losh, M Schantell… - Brain, 2022 - academic.oup.com
An extensive electrophysiological literature has proposed a pathological 'slowing'of
neuronal activity in patients on the Alzheimer's disease spectrum. Supported by numerous …

Transcranial stimulation of alpha oscillations up-regulates the default mode network

KJ Clancy, JA Andrzejewski, Y You… - Proceedings of the …, 2022 - National Acad Sciences
The default mode network (DMN) is the most-prominent intrinsic connectivity network,
serving as a key architecture of the brain's functional organization. Conversely, dysregulated …

Machine learning algorithms and statistical approaches for Alzheimer's disease analysis based on resting-state EEG recordings: A systematic review

KD Tzimourta, V Christou, AT Tzallas… - … journal of neural …, 2021 - World Scientific
Alzheimer's Disease (AD) is a neurodegenerative disorder and the most common type of
dementia with a great prevalence in western countries. The diagnosis of AD and its …

[HTML][HTML] An update on the use of gamma (multi) sensory stimulation for Alzheimer's disease treatment

V Manippa, A Palmisano, M Filardi, D Vilella… - Frontiers in Aging …, 2022 - frontiersin.org
Alzheimer's disease (AD) is characterized by reduced fast brain oscillations in the gamma
band (γ,> 30 Hz). Several animal studies show that inducing gamma oscillations through …

Neurotransmitters in prevention and treatment of Alzheimer's disease

Z Yang, Y Zou, L Wang - International Journal of Molecular Sciences, 2023 - mdpi.com
Alzheimer's disease (AD) is the most frequent cause of cognitive impairment in middle-aged
and older populations. There is a lack of drugs that demonstrate significant efficacy in AD, so …

Cognitive and neuropathophysiological outcomes of gamma-tACS in dementia: a systematic review

V Manippa, A Palmisano, MA Nitsche, M Filardi… - Neuropsychology …, 2024 - Springer
Despite the numerous pharmacological interventions targeting dementia, no disease-
modifying therapy is available, and the prognosis remains unfavorable. A promising …