Neuroendocrine tumors (NETs) are heterogeneous malignancies arising from the diffuse
neuroendocrine system. They frequently originate in the gastroenteropancreatic (GEP) tract …

Multiple endocrine neoplasia type 1 (MEN1), a rare tumor syndrome that is inherited in an
autosomal dominant pattern, is continuing to raise great interest for endocrinology …

Chromatin-binding proteins are critical regulators of cell state in haematopoiesis,. Acute
leukaemias driven by rearrangement of the mixed lineage leukaemia 1 gene (KMT2A r) or …

Menin inhibitors are novel targeted agents currently in clinical development for the treatment
of genetically defined subsets of acute leukemia. Menin has a tumor suppressor function in …

Objective: The aim was to provide guidelines for evaluation, treatment, and genetic testing
for multiple endocrine neoplasia type 1 (MEN1). Participants: The group, which comprised …

Multiple endocrine neoplasia type 1 (MEN1) is a rare hereditary tumor syndrome inherited in
an autosomal dominant manner and characterized by a predisposition to a multitude of …

Gastroenteropancreatic (GEP) neuroendocrine neoplasms (NENs) are heterogeneous
regarding site of origin, biological behavior, and malignant potential. There has been a rapid …

Primary hyperparathyroidism (PHPT) is a common disorder in which parathyroid hormone
(PTH) is excessively secreted from one or more of the four parathyroid glands. A single …

The better understanding of the biological behavior of multiple endocrine neoplasia type 1
(MEN1) organ manifestations and the increase in clinical experience warrant a revision of …

Multiple endocrine neoplasia (MEN) is characterized by the occurrence of tumors involving
two or more endocrine glands within a single patient. Four major forms of MEN, which are …