[HTML][HTML] The pathophysiology, diagnosis, and management of sepsis-associated disseminated intravascular coagulation

T Iba, J Helms, JM Connors, JH Levy - Journal of Intensive Care, 2023 - Springer
Abstract Background The International Society on Thrombosis and Haemostasis (ISTH)
released overt disseminated intravascular coagulation (DIC) diagnostic criteria in 2001 …

[HTML][HTML] Dysregulation of neutrophil death in sepsis

C Zhu, Y Wang, Q Liu, H Li, C Yu, P Li, X Deng… - Frontiers in …, 2022 - frontiersin.org
Sepsis is a prevalent disease that has alarmingly high mortality rates and, for several
survivors, long-term morbidity. The modern definition of sepsis is an aberrant host response …

Neutralization of NET-associated human ARG1 enhances cancer immunotherapy

S Canè, RM Barouni, M Fabbi, J Cuozzo… - Science translational …, 2023 - science.org
Myeloid cells can restrain antitumor immunity by metabolic pathways, such as the
degradation of l-arginine, whose concentrations are regulated by the arginase 1 (ARG1) …

[图书][B] Wintrobe's clinical hematology

MM Wintrobe - 2009 - books.google.com
Now available in a thoroughly revised Twelfth Edition, Wintrobe's Clinical Hematology
continues to be an industry leader with its ability to correlate basic science with the clinical …

Neutrophil and remnant clearance in immunity and inflammation

A Singhal, S Kumar - Immunology, 2022 - Wiley Online Library
Neutrophil‐centred inflammation and flawed clearance of neutrophils cause and exuberate
multiple pathological conditions. These most abundant leukocytes exhibit very high daily …

Pyroptosis in neutrophils: multimodal integration of inflammasome and regulated cell death signaling pathways

GR Dubyak, BA Miller, E Pearlman - Immunological reviews, 2023 - Wiley Online Library
Pyroptosis is a proinflammatory mode of lytic cell death mediated by accumulation of plasma
membrane (PM) macropores composed of gasdermin‐family (GSDM) proteins. It facilitates …

[HTML][HTML] Neutrophils' extracellular trap mechanisms: from physiology to pathology

J Schoen, M Euler, C Schauer, G Schett… - International Journal of …, 2022 - mdpi.com
Neutrophils are an essential part of the innate immune system and the first line of defense
against invading pathogens. They phagocytose, release granular contents, produce reactive …

Mechanisms regulating neutrophil responses in immunity, allergy, and autoimmunity

A Özcan, O Boyman - Allergy, 2022 - Wiley Online Library
Neutrophil granulocytes, or neutrophils, are the most abundant circulating leukocytes in
humans and indispensable for antimicrobial immunity, as exemplified in patients with inborn …

Single‐cell RNA sequencing reveals cellular and molecular reprograming landscape of gliomas and lung cancer brain metastases

HF Sun, LD Li, IW Lao, X Li, BJ Xu… - Clinical and …, 2022 - Wiley Online Library
Background Brain malignancies encompass gliomas and brain metastases originating from
extracranial tumours including lung cancer. Approximately 50% of patients with lung …

[HTML][HTML] Relationship between neuroglial apoptosis and neuroinflammation in the epileptic focus of the brain and in the blood of patients with drug-resistant epilepsy

TV Sokolova, YM Zabrodskaya, AV Litovchenko… - International Journal of …, 2022 - mdpi.com
Neuroglial apoptosis and neuroinflammation play an important role in epileptogenesis. The
aim of this study is to evaluate neuronal and glial apoptosis in association with …