Taxol (paclitaxel), the most well-known taxane diterpenoid, is the best-selling natural-source
anticancer drug ever produced and one of the most common prescriptions in the treatment of …

The pool of abundant chiral terpene building blocks (ie,“chiral pool terpenes”) has long
served as a starting point for the chemical synthesis of complex natural products, including …

Taxol is one of the most famous natural diterpenoids and an important anticancer medicine.
Taxol represents a formidable synthetic challenge and has prompted significant interest from …

Radical fragment coupling reactions that unite intricate subunits have become an important
class of transformations within the arena of complex molecule synthesis. This Perspective …

Achieving convergent synthetic strategies has long been a gold standard in constructing
complex molecular skeletons, allowing for the rapid generation of complexity in …

We report here a catalytic method for the modular ring expansion of cyclic aliphatic alcohols.
In this work, proton-coupled electron transfer activation of an allylic alcohol substrate affords …

Taxol (1) is a clinically used antineoplastic diterpenoid. The tetracyclic ring system
comprises a 6/8/6-membered carbocycle (ABC-ring) and a fused oxetane ring (D-ring) …

Terpenoids are a very prominent class of natural compounds produced in diverse genera of
plants, fungi, algae and sponges. They gained significant pharmaceutical value since …

Rhamnofolane, tigliane, and daphnane diterpenoids are structurally complex natural
products with multiple oxygen functionalities, making them synthetically challenging. While …

Batrachotoxin is an extremely potent cardio‐and neurotoxic steroidal alkaloid found in
certain species of frogs, birds, and beetles. The steroidal 6/6/6/5‐membered carbocycle …