The chronic inflammatory response within the airways of asthmatics is associated with
structural changes termed airway remodeling. This remodeling process is a key feature of …

Human asthma is a complex and heterogeneous disorder characterized by chronic
inflammation, bronchospasm and airway remodeling. The latter is a major determinant of the …

Background There is a paucity of studies comparing asthma and chronic obstructive
pulmonary disease (COPD) based on thoracic quantitative computed tomographic (QCT) …

Background Imaging variables, including airway diameter, wall thickness, and air trapping,
have been found to be important metrics when differentiating patients with severe asthma …

Background Asthma heterogeneity is multidimensional and requires additional tools to
unravel its complexity. Computed tomography (CT)–assessed proximal airway remodeling …

Background: Airway remodeling (AR) is a prominent feature of asthma and other obstructive
lung diseases that is minimally affected by current treatments. The goals of this Official …

The ability of human tissue to reorganize and restore its existing structure underlies tissue
homeostasis in the healthy airways, but in disease can persist without normal resolution …

Background Severe asthma is a heterogeneous condition. Airway remodelling is a feature of
severe asthma and can be determined by the assessment of high-resolution computed …

Asthma remains a major health problem with significant morbidity, mortality and economic
costs. In asthma, airway remodelling, which refers to all the microscopic structural changes …

Chronic obstructive pulmonary disease (COPD) is an increasing cause of morbidity and
mortality worldwide and results in substantial social and economic burdens. COPD is a …