[HTML][HTML] Redox regulation of the immune response

G Morris, M Gevezova, V Sarafian… - Cellular & Molecular …, 2022 - nature.com
The immune-inflammatory response is associated with increased nitro-oxidative stress. The
aim of this mechanistic review is to examine:(a) the role of redox-sensitive transcription …

[HTML][HTML] The metabolic signature of macrophage responses

A Viola, F Munari, R Sánchez-Rodríguez… - Frontiers in …, 2019 - frontiersin.org
Macrophages are a heterogeneous population of immune cells playing several and diverse
functions in homeostatic and immune responses. The broad spectrum of macrophage …

Lipid metabolism in regulation of macrophage functions

J Yan, T Horng - Trends in cell biology, 2020 - cell.com
Macrophages are cells of the innate immune system that regulate the maintenance of tissue
homeostasis, host defense during pathogen infection, and tissue repair in response to tissue …

Lipid metabolism and Alzheimer's disease: clinical evidence, mechanistic link and therapeutic promise

F Yin - The FEBS journal, 2023 - Wiley Online Library
Alzheimer's disease (AD) is an age‐associated neurodegenerative disorder with
multifactorial etiology, intersecting genetic and environmental risk factors, and a lack of …

[HTML][HTML] Lipid metabolism reprogramming and its potential targets in cancer

C Cheng, F Geng, X Cheng, D Guo - Cancer communications, 2018 - Springer
Reprogramming of lipid metabolism is a newly recognized hallmark of malignancy.
Increased lipid uptake, storage and lipogenesis occur in a variety of cancers and contribute …

[HTML][HTML] Apolipoprotein E in lipid metabolism and neurodegenerative disease

LG Yang, ZM March, RA Stephenson… - Trends in Endocrinology & …, 2023 - cell.com
Dysregulation of lipid metabolism has emerged as a central component of many
neurodegenerative diseases. Variants of the lipid transport protein, apolipoprotein E …

[HTML][HTML] Lipid signaling and lipotoxicity in metaflammation: indications for metabolic disease pathogenesis and treatment

ME Ertunc, GS Hotamisligil - Journal of lipid research, 2016 - ASBMB
Lipids encompass a wide variety of molecules such as fatty acids, sterols, phospholipids,
and triglycerides. These molecules represent a highly efficient energy resource and can act …

[HTML][HTML] Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in …

P Godoy, NJ Hewitt, U Albrecht, ME Andersen… - Archives of …, 2013 - Springer
This review encompasses the most important advances in liver functions and hepatotoxicity
and analyzes which mechanisms can be studied in vitro. In a complex architecture of nested …

[HTML][HTML] Immune regulation of metabolic homeostasis in health and disease

JR Brestoff, D Artis - Cell, 2015 - cell.com
Obesity is an increasingly prevalent disease worldwide. While genetic and environmental
factors are known to regulate the development of obesity and associated metabolic …

Dietary supplementation of bile acid attenuate adverse effects of high-fat diet on growth performance, antioxidant ability, lipid accumulation and intestinal health in …

P Yin, S Xie, Z Zhuang, X He, X Tang, L Tian, Y Liu… - Aquaculture, 2021 - Elsevier
Bile acid (BA) has been reported to improve growth performance and play an important role
in lipid metabolism of fish. Five diets were formulated to investigate the effects of dietary bile …