[HTML][HTML] Interplay of oxidative stress, cellular communication and signaling pathways in cancer

MJ Iqbal, A Kabeer, Z Abbas, HA Siddiqui… - Cell Communication and …, 2024 - Springer
Cancer remains a significant global public health concern, with increasing incidence and
mortality rates worldwide. Oxidative stress, characterized by the production of reactive …

[HTML][HTML] Exosomes-Mediated Signaling Pathway: A New Direction for Treatment of Organ Ischemia-Reperfusion Injury

Y Wang, R Xu, Y Yan, B He, C Miao, Y Fang, H Wan… - Biomedicines, 2024 - mdpi.com
Ischemia reperfusion (I/R) is a common pathological process which occurs mostly in organs
like the heart, brain, kidney, and lung. The injury caused by I/R gradually becomes one of …

Contribution of Immune Responses to the Cardiotoxicity and Hepatotoxicity of Deltamethrin in Early Life Stage Zebrafish (Danio rerio)

J Wang, H Li, Y Liu, NE Andrzejczyk… - Environmental …, 2024 - ACS Publications
Deltamethrin (DM) is a widely used insecticide that has demonstrated developmental toxicity
in the early life stages of fish. To better characterize the underlying mechanisms, embryos …

[HTML][HTML] Effects of Akt Activator SC79 on Human M0 Macrophage Phagocytosis and Cytokine Production

RJ Lee, ND Adappa, JN Palmer - Cells, 2024 - mdpi.com
Akt is an important kinase in metabolism. Akt also phosphorylates and activates endothelial
and neuronal nitric oxide (NO) synthases (eNOS and nNOS, respectively) expressed in M0 …

[HTML][HTML] Oxidative Stress and Redox-Dependent Pathways in Cholangiocarcinoma

A Caligiuri, M Becatti, N Porro, S Borghi, F Marra… - Antioxidants, 2023 - mdpi.com
Cholangiocarcinoma (CCA) is a primary liver tumor that accounts for 2% of all cancer-
related deaths worldwide yearly. It can arise from cholangiocytes of biliary tracts, peribiliary …

[HTML][HTML] Exosomes: compositions, biogenesis, and mechanisms in diabetic wound healing

Y Li, Z Zhu, S Li, X Xie, L Qin, Q Zhang, Y Yang… - Journal of …, 2024 - Springer
Diabetic wounds are characterized by incomplete healing and delayed healing, resulting in
a considerable global health care burden. Exosomes are lipid bilayer structures secreted by …

[HTML][HTML] The Triterpenoid CDDO-Methyl Ester Reduces Tumor Burden, Reprograms the Immune Microenvironment, and Protects from Chemotherapy-Induced Toxicity …

JA Moerland, KT Liby - Antioxidants, 2024 - mdpi.com
NRF2 activation protects epithelial cells from malignancy, but cancer cells can upregulate
the pathway to promote survival. NRF2 activators including CDDO-Methyl ester (CDDO-Me) …

[HTML][HTML] Investigation of Epilobium hirsutum L. Optimized Extract's Anti-Inflammatory and Antitumor Potential

AM Vlase, A Toiu, O Gligor, D Muntean, T Casian… - Plants, 2024 - mdpi.com
Epilobium hirsutum L., commonly known as hairy willowherb, is a perennial herbaceous
plant native to Europe and Asia. In Romania, the Epilobium genus includes 17 species that …