Bioinspired polymer vesicles and membranes for biological and medical applications
Biological membranes play an essential role in living organisms by providing stable and
functional compartments, preserving cell architecture, whilst supporting signalling and …
functional compartments, preserving cell architecture, whilst supporting signalling and …
[HTML][HTML] Chemistry and engineering of brush type polymers: Perspective towards tissue engineering
In tissue engineering, it is imperative to control the behaviour of cells/stem cells, such as
adhesion, proliferation, propagation, motility, and differentiation for tissue regeneration …
adhesion, proliferation, propagation, motility, and differentiation for tissue regeneration …
Ca2+-Daptomycin targets cell wall biosynthesis by forming a tripartite complex with undecaprenyl-coupled intermediates and membrane lipids
F Grein, A Müller, KM Scherer, X Liu, KC Ludwig… - Nature …, 2020 - nature.com
The lipopeptide daptomycin is used as an antibiotic to treat severe infections with gram-
positive pathogens, such as methicillin resistant Staphylococcus aureus (MRSA) and drug …
positive pathogens, such as methicillin resistant Staphylococcus aureus (MRSA) and drug …
Supramolecular assemblies underpin turnover of outer membrane proteins in bacteria
P Rassam, NA Copeland, O Birkholz, C Tóth… - Nature, 2015 - nature.com
Gram-negative bacteria inhabit a broad range of ecological niches. For Escherichia coli, this
includes river water as well as humans and animals, where it can be both a commensal and …
includes river water as well as humans and animals, where it can be both a commensal and …
Hydrophobic mismatch sorts SNARE proteins into distinct membrane domains
The clustering of proteins and lipids in distinct microdomains is emerging as an important
principle for the spatial patterning of biological membranes. Such domain formation can be …
principle for the spatial patterning of biological membranes. Such domain formation can be …
Structural and mechanistic analysis of a tripartite ATP-independent periplasmic TRAP transporter
Tripartite ATP-independent periplasmic (TRAP) transporters are found widely in bacteria
and archaea and consist of three structural domains, a soluble substrate-binding protein (P …
and archaea and consist of three structural domains, a soluble substrate-binding protein (P …
Diffusion and capture permits dynamic coupling between treadmilling FtsZ filaments and cell division proteins
Most bacteria accomplish cell division with the help of a dynamic protein complex called the
divisome, which spans the cell envelope in the plane of division. Assembly and activation of …
divisome, which spans the cell envelope in the plane of division. Assembly and activation of …
Biomimetic particles as therapeutics
In recent years, there have been major advances in the development of novel nanoparticle-
and microparticle-based therapeutics. An emerging paradigm is the incorporation of …
and microparticle-based therapeutics. An emerging paradigm is the incorporation of …
[HTML][HTML] Biopores/membrane proteins in synthetic polymer membranes
M Garni, S Thamboo, CA Schoenenberger… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Background Mimicking cell membranes by simple models based on the reconstitution of
membrane proteins in lipid bilayers represents a straightforward approach to understand …
membrane proteins in lipid bilayers represents a straightforward approach to understand …
Preserved transmembrane protein mobility in polymer-supported lipid bilayers derived from cell membranes
H Pace, L Simonsson Nyström… - Analytical …, 2015 - ACS Publications
Supported lipid bilayers (SLBs) have contributed invaluable information about the
physiochemical properties of cell membranes, but their compositional simplicity often limits …
physiochemical properties of cell membranes, but their compositional simplicity often limits …