Cryptococcus neoformans (C. neoformans) is a pathogenic fungus with a global distribution.
Humans become infected by inhaling the fungus from the environment, and the fungus …

Cryptococcosis is caused by the fungal genus Cryptococcus. Cryptococcosis, predominantly
meningoencephalitis, emerged with the HIV pandemic, primarily afflicting HIV-infected …

In the murine model of Cryptococcus neoformans infection Th1 (IL-12/IFN-γ) and Th17 (IL-
23/IL-17) responses are associated with protection, whereas an IL-4-dependent Th2 …

Understanding the host immune response during cryptococcal meningitis (CM) is of critical
importance for the development of immunomodulatory therapies. We profiled the …

Background. Correlates of immune protection in patients with human immunodeficiency
virus (HIV)–associated cryptococcal meningitis are poorly defined. A clearer understanding …

Cryptococcosis is a systemic fungal infection caused by Cryptococcus neoformans. In
immunocompetent patients, cryptococcal infection is often confined to the lungs. In …

Cryptococcus neoformans is a major fungal pathogen that disseminates to the central
nervous system (CNS) to cause fatal meningoencephalitis, but little is known about immune …

The vast majority of infection with cryptococcal species occurs with Cryptococcus
neoformans in the severely immunocompromised. A significant exception to this is the …

Invasive fungal infections are emerging diseases that kill over 1.5 million people per year
worldwide. With the increase of immunocompromised populations, the incidence of invasive …

The Cryptococcus neoformans/Cryptococcus gattii species complex is a group of fungal
pathogens with different phenotypic and genotypic diversity that cause disease in …