The immune events that take place in the central nervous system (CNS) during cryptococcal
infection are incompletely understood. We used competitive reverse transcription-PCR to …

The brain represents a significant barrier for protective immune responses in both infectious
disease and cancer. We have recently demonstrated that immunotherapy with anti-CD40 …

Cryptococcus neoformans is a significant cause of fungal meningitis in patients with
impaired T cell-mediated immunity (CMI). Experimental pulmonary infection with a C …

Scavenger receptors represent an important class of pattern recognition receptors shown to
mediate both beneficial and detrimental roles in host defense against microbial pathogens …

Introduction. Cryptococcosis is a ubiquitous opportunistic fungal disease caused by
Cryptococcus neoformans var. grubii. It has high global morbidity and mortality among HIV …

The severity of cryptococcosis in lupus from varying genetic-backgrounds might be different
due to the heterogeneity of lupus-pathogenesis. This study explored cryptococcosis in lupus …

Cryptococcosis is a life-threatening disease caused by the encapsulated yeast,
Cryptococcus neoformans. Although infection with C. neoformans is initiated in the lungs …

Abstract Background/Aims: Cryptococcus neoformans infections are becoming increasingly
prevalent and remain a life-threatening clinical issue in immune-compromised hosts. The …

The interaction of pathogenic Cryptococcus species with their various hosts is somewhat
unique compared to other fungal pathogens such as Aspergillus fumigatus and Candida …

Cryptococcosis is an important complication of solid-organ transplantation, but the risk
factors for disease are poorly understood. The goal of this study was to investigate whether …