The emerging era of personalized medicine in advanced colorectal cancer
CWK Wu, M Reid, S Leedham… - … of gastroenterology and …, 2022 - Wiley Online Library
Colorectal cancer (CRC) is a genetically heterogeneous disease with its pathogenesis often
driven by varying genetic or epigenetic alterations. This has led to a substantial number of …
driven by varying genetic or epigenetic alterations. This has led to a substantial number of …
Role of gremlin-1 in the pathophysiology of the adipose tissues
E Grillo, C Ravelli, G Colleluori, F D'Agostino… - Cytokine & Growth …, 2023 - Elsevier
Gremlin-1 is a secreted bone morphogenetic protein (BMP) antagonist playing a pivotal role
in the regulation of tissue formation and embryonic development. Since its first identification …
in the regulation of tissue formation and embryonic development. Since its first identification …
[HTML][HTML] Gremlin-1 in pregnancy and postpartum: relation to the fatty liver index, markers of bone health, glucose metabolism and gestational diabetes mellitus status
C Deischinger, M Bastian, K Leitner… - Acta Diabetologica, 2023 - Springer
Introduction Gremlin-1 is a peptide that functions as an antagonist to bone morphogenic
proteins and is overexpressed in obesity and type 2 diabetes mellitus. Gremlin-1 has not yet …
proteins and is overexpressed in obesity and type 2 diabetes mellitus. Gremlin-1 has not yet …
Discovery of ginisortamab, a potent and novel anti-gremlin-1 antibody in clinical development for the treatment of cancer
GCG Davies, N Dedi, PS Jones, L Kevorkian… - Mabs, 2023 - Taylor & Francis
ABSTRACT Gremlin-1, a high-affinity antagonist of bone morphogenetic proteins (BMP)-2,−
4, and− 7, is implicated in tumor initiation and progression. Increased gremlin-1 expression …
4, and− 7, is implicated in tumor initiation and progression. Increased gremlin-1 expression …
[HTML][HTML] GREM1 signaling in cancer: tumor promotor and suppressor?
Z Gao, JM Houthuijzen, P Ten Dijke… - Journal of Cell …, 2023 - Springer
Abstract GREMLIN1 (GREM1) is member of a family of structurally and functionally related
secreted cysteine knot proteins, which act to sequester and inhibit the action of …
secreted cysteine knot proteins, which act to sequester and inhibit the action of …
Long noncoding RNA long intergenic non-protein-coding RNA 173 contributes to nasopharyngeal carcinoma progression by regulating microRNA-765/Gremlin 1 …
D Wang, H Jiang - Human & Experimental Toxicology, 2023 - journals.sagepub.com
Background Long intergenic non-protein-coding RNA 173 (LINC00173) executes vital
functions in various cancers. Nevertheless, its role and expression in nasopharyngeal …
functions in various cancers. Nevertheless, its role and expression in nasopharyngeal …
[HTML][HTML] An Ensemble Learning-based Framework from Multicohort Reveals the Molecular Mechanism of GREM1 in Endometrial Cancer
Y Zhu, H Wang, Y Zu - Gene Expression, 2023 - xiahepublishing.com
Methods The training and test cohorts were gathered from The Cancer Genome Atlas and
Genome Expression Omnibus databases, respectively. The cohorts were divided into low …
Genome Expression Omnibus databases, respectively. The cohorts were divided into low …
[PDF][PDF] State-of-the-art of the Bone Morphogenetic Protein research field: 13th International BMP Confer-ence
Te 13th International BMP Conference was held in October 2022 in Dubrovnik. Te
conference was attended by more than 240 participants from North America, Europe, Asia …
conference was attended by more than 240 participants from North America, Europe, Asia …
Recent research progress from biological perspective on the mechanism of formation of osteoarthritis after anterior cruciate ligament injury.
Z Kai, DU Xiu-pan, W Guang-ji - Journal of Hainan Medical …, 2024 - search.ebscohost.com
The anterior cruciate ligament (ACL) mainly plays a role in stabilizing the knee joint by
limiting the forward translation of tibial force and rotational force at the tibial joint, and if this …
limiting the forward translation of tibial force and rotational force at the tibial joint, and if this …
State-of-the-art of the Bone Morphogenetic Protein research field: 13th International BMP Conference, Dubrovnik 2022
Sažetak The 13th International BMP Conference was held in October 2022 in Dubrovnik.
The conference was attended by more than 240 participants from North America, Europe …
The conference was attended by more than 240 participants from North America, Europe …