Blood–brain barrier link to human cognitive impairment and Alzheimer's disease
Vascular dysfunction is frequently observed in disorders associated with cognitive
impairment, dementia and Alzheimer's disease (AD). Recent advances in neuroimaging and …
impairment, dementia and Alzheimer's disease (AD). Recent advances in neuroimaging and …
Physiology and clinical relevance of enlarged perivascular spaces in the aging brain
Perivascular spaces (PVS) are fluid-filled compartments that are part of the cerebral blood
vessel wall and represent the conduit for fluid transport in and out of the brain. PVS are …
vessel wall and represent the conduit for fluid transport in and out of the brain. PVS are …
Association of enlarged perivascular spaces and measures of small vessel and Alzheimer disease
EC Gertje, D van Westen, C Panizo… - Neurology, 2021 - AAN Enterprises
Objective To investigate the relationship between enlarged perivascular spaces (EPVS) and
measures of Alzheimer disease (AD), small vessel disease (SVD), cognition, vascular risk …
measures of Alzheimer disease (AD), small vessel disease (SVD), cognition, vascular risk …
Cognitive impairment caused by hypoxia: from clinical evidences to molecular mechanisms
X Wang, L Cui, X Ji - Metabolic Brain Disease, 2022 - Springer
Hypoxia is a state of reduced oxygen supply and excessive oxygen consumption. According
to the duration of hypoxic period, it can be classified as acute and chronic hypoxia. Both …
to the duration of hypoxic period, it can be classified as acute and chronic hypoxia. Both …
Volumetric distribution of perivascular space in relation to mild cognitive impairment
Vascular contributions to early cognitive decline are increasingly recognized, prompting
further investigation into the nature of related changes in perivascular spaces (PVS). Using …
further investigation into the nature of related changes in perivascular spaces (PVS). Using …
The role of brain perivascular space burden in early-stage Parkinson's disease
T Shen, Y Yue, S Zhao, J Xie, Y Chen, J Tian… - NPJ Parkinson's …, 2021 - nature.com
Perivascular space (PVS) is associated with neurodegenerative diseases, while its effect on
Parkinson's disease (PD) remains unclear. We aimed to investigate the clinical and …
Parkinson's disease (PD) remains unclear. We aimed to investigate the clinical and …
Why are perivascular spaces important?
T Shulyatnikova, MR Hayden - Medicina, 2023 - mdpi.com
Perivascular spaces (PVS) and their enlargement (EPVS) have been gaining interest as
EPVS can be visualized non-invasively by magnetic resonance imaging (MRI) when viewing …
EPVS can be visualized non-invasively by magnetic resonance imaging (MRI) when viewing …
Neuropathologic and cognitive correlates of enlarged perivascular spaces in a community-based cohort of older adults
C Javierre-Petit, JA Schneider, A Kapasi, N Makkinejad… - Stroke, 2020 - Am Heart Assoc
Background and Purpose: Enlarged perivascular spaces (EPVS) have been associated with
aging, increased stroke risk, decreased cognitive function, and vascular dementia. However …
aging, increased stroke risk, decreased cognitive function, and vascular dementia. However …
Brain Injury: Response to Injury Wound-Healing Mechanisms and Enlarged Perivascular Spaces in Obesity, Metabolic Syndrome, and Type 2 Diabetes Mellitus
MR Hayden - Medicina, 2023 - mdpi.com
Embryonic genetic mechanisms are present in the brain and ready to be placed into action
upon cellular injury, termed the response to injury wound-healing (RTIWH) mechanism …
upon cellular injury, termed the response to injury wound-healing (RTIWH) mechanism …
[HTML][HTML] Heterogeneity of white matter hyperintensities in cognitively impaired patients with cerebral small vessel disease
T Wang, A Jin, Y Fu, Z Zhang, S Li, D Wang… - Frontiers in …, 2021 - frontiersin.org
Objective Similar white matter hyperintensities (WMH) might have different impact on the
cognitive outcomes in patients with cerebral small vessel disease (CSVD). This study is to …
cognitive outcomes in patients with cerebral small vessel disease (CSVD). This study is to …