Ocular novel drug delivery: impacts of membranes and barriers
Background: Ocular drug delivery is an extremely challenging area due to its restrictive
barrier functionalities. Objective: Drug transport via corneal/non-corneal routes involves …
barrier functionalities. Objective: Drug transport via corneal/non-corneal routes involves …
Systemic absorption of topically applied ocular drugs in humans
L SALMINEN - Journal of Ocular Pharmacology and Therapeutics, 1990 - liebertpub.com
Literature on human plasma concentrations after instillation of ocular timolol, levobunolol,
atropine, cyclopentolate, scopolamine, phenylephrine, betamethasone and technetium Tc …
atropine, cyclopentolate, scopolamine, phenylephrine, betamethasone and technetium Tc …
Ocular drug delivery: impact of in vitro cell culture models
A Solanki, S Desai, A Grover, A Hirani, Y Pathak… - Nano-Biomaterials For …, 2016 - Springer
The physiological characteristics make effective drug delivery very challenging. Various
structures such as the cornea, conjunctival epithelium, blood-retinal barrier (BRB), and the …
structures such as the cornea, conjunctival epithelium, blood-retinal barrier (BRB), and the …
Comparison of 2.5% and 10% phenylephrine in the elevation of upper eyelids with ptosis
HJ Glatt, DR Fett, AM Putterman - Ophthalmic Surgery, Lasers …, 1990 - journals.healio.com
The Mueller's muscle-conjunctival resection procedure has been effective in treating ptosis
in eyelids that elevate upon instillation of topical 10% phenylephrine (Neo-Synephrine). The …
in eyelids that elevate upon instillation of topical 10% phenylephrine (Neo-Synephrine). The …
Recent advances in drug design and delivery across biological barriers using computational models
A Garg, HK Dewangan - Letters in Drug Design & Discovery, 2022 - ingentaconnect.com
The systemic delivery of pharmacological substances generally exhibits several significant
limitations associated with the bio-distribution of active drugs in the body. Human body's …
limitations associated with the bio-distribution of active drugs in the body. Human body's …
The effect of topical ophthalmic instillation of timolol and betaxolol on lung function in asthmatic subjects
TL Dunn, MJ Gerber, AS Shen… - American Review of …, 1986 - atsjournals.org
The propensity of systemic beta-adrenergic blockers to cause bronchoconstriction in
patients with reactive airway disease is well recognized. A study was carried out to …
patients with reactive airway disease is well recognized. A study was carried out to …
Microbial keratitis in children
LD Ormerod, AL Murphree, DS Gomez, DJ Schanzlin… - Ophthalmology, 1986 - Elsevier
Forty-seven eyes with microbial keratitis occurring in 44 children under 16 years of age were
studied. Under the age of three, 92% of the infections involved Pseudomonas aeruginosa …
studied. Under the age of three, 92% of the infections involved Pseudomonas aeruginosa …
[PDF][PDF] The challenges of ophthalmic drug delivery: a review
During the past decades, researchers involved in the development of ophthalmic
pharmaceuticals have understood that ophthalmic drug delivery is a challenging subject for …
pharmaceuticals have understood that ophthalmic drug delivery is a challenging subject for …
Ocular barriers
Drugs for ocular administration are administered topically and their absorption is limited by
different barriers known as ocular barriers. These barriers are located in different areas of …
different barriers known as ocular barriers. These barriers are located in different areas of …
[HTML][HTML] Impacts of nanomedicines in ocular pharmacotherapy
A Nakhlband, J Barar - BioImpacts: BI, 2011 - ncbi.nlm.nih.gov
Methods Recent published articles related to applications of ocular nanomedicines were
reviewed and highlighted in this review article. Results It seems the emergence of …
reviewed and highlighted in this review article. Results It seems the emergence of …