RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …

Abstract Narcolepsy type 1 (NT1) is a chronic sleep disorder resulting from the loss of a
small population of hypothalamic neurons that produce wake-promoting hypocretin (HCRT; …

Multiple sclerosis (MS) involves the infiltration of autoreactive T cells into the CNS, yet we
lack a comprehensive understanding of the signaling pathways that regulate this process …

Multiple sclerosis (MS) is an incurable autoimmune disease and is currently treated by
systemic immunosuppressants with off-target side effects. Although aberrant myeloid …

Autoimmune diseases (AIDs) are the consequence of a breach in immune tolerance,
leading to the inability to sufficiently differentiate between self and non-self. Immune …

Peripheral central nervous system (CNS)–infiltrating lymphocytes are a hallmark of
relapsing-remitting multiple sclerosis. Tissue-resident memory T cells (TRM) not only …

Multiple sclerosis (MS) is a neuro-inflammatory and neurodegenerative disease that is most
prevalent in Northern Europe. Although it is known that inherited risk for MS is located within …

CNS-resident macrophages—including parenchymal microglia and border-associated
macrophages (BAMs)—contribute to neuronal development and health, vascularization, and …

Autophagy comprises a growing range of cellular pathways, which occupy central roles in
response to energy deprivation, organelle turnover and proteostasis. Over the years …

In recent years, microRNAs (miRNAs) have gained increased attention from researchers
around the globe. Although it is twenty nucleotides long, it can modulate several gene …