COVID-19 convalescent plasma for the treatment of immunocompromised patients: a systematic review and meta-analysis

JW Senefeld, M Franchini, C Mengoli… - JAMA Network …, 2023 - jamanetwork.com
Importance Patients who are immunocompromised have increased risk for morbidity and
mortality associated with coronavirus disease 2019 (COVID-19) because they less …

COVID-19 convalescent plasma and clinical trials: understanding conflicting outcomes

D Focosi, M Franchini, L Pirofski… - Clinical microbiology …, 2022 - Am Soc Microbiol
Convalescent plasma (CP) recurs as a frontline treatment in epidemics because it is
available as soon as there are survivors. The COVID-19 pandemic represented the first …

Passive immunotherapy against SARS-CoV-2: from plasma-based therapy to single potent antibodies in the race to stay ahead of the variants

WR Strohl, Z Ku, Z An, SF Carroll, BA Keyt, LM Strohl - BioDrugs, 2022 - Springer
The COVID-19 pandemic is now approaching 2 years old, with more than 440 million people
infected and nearly six million dead worldwide, making it the most significant pandemic …

[HTML][HTML] SARS-CoV-2 neutralising antibody testing in Europe: towards harmonisation of neutralising antibody titres for better use of convalescent plasma and …

D Nguyen, P Simmonds, M Steenhuis… - …, 2021 - eurosurveillance.org
We compared the performance of SARS-CoV-2 neutralising antibody testing between 12
European laboratories involved in convalescent plasma trials. Raw titres differed almost 100 …

Clinical management of patients with B-cell depletion agents to treat or prevent prolonged and severe SARS-COV-2 infection: defining a treatment pathway

A D'Abramo, S Vita, G Maffongelli… - Frontiers in …, 2022 - frontiersin.org
Introduction Immunocompromised patients with B-cell depletion agents are at risk for
persistence and/or severe SARS-COV-2 infection. We describe a case series of 21 COVID …

Safety and efficacy of convalescent plasma in COVID-19: an overview of systematic reviews

M Franchini, F Corsini, D Focosi, M Cruciani - Diagnostics, 2021 - mdpi.com
Convalescent plasma (CP) from patients recovered from COVID-19 is one of the most
studied anti-viral therapies against SARS-COV-2 infection. The aim of this study is to …

Combined antiviral therapy as effective and feasible option in allogenic hematopoietic stem cell transplantation during SARS-COV-2 infection: a case report

S Vita, A D'Abramo, A Coppola, C Farroni… - Frontiers in …, 2024 - frontiersin.org
Here we describe the case of a 51 years old Italian woman with acute lymphoblastic
leukemia who underwent to hematopoietic stem cell transplantation (HSCT) during SARS …

Hyperimmune Plasma and Immunoglobulins against COVID-19: a narrative review

M Franchini, D Focosi - Life, 2024 - mdpi.com
Since late 2019, the new SARS-CoV-2 virus belonging to the Coronaviridae family has been
responsible for COVID-19 pandemic, a severe acute respiratory syndrome. Several antiviral …

[HTML][HTML] Lessons learned from the use of convalescent plasma for the treatment of COVID-19 and specific considerations for immunocompromised patients

M Beraud, EG Meyer, M Lozano, A Bah… - … and Apheresis Science, 2022 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) convalescent plasma (CovCP) infusions
have been widely used for the treatment of hospitalized patients with COVID-19. The aims of …

Clinical and virological response to convalescent plasma in a chronic lymphocytic leukemia patient with COVID-19 pneumonia

G Belcari, A Conti, A Mazzoni, M Lanza, P Mazzetti… - Life, 2022 - mdpi.com
The burden of COVID-19 remains unchanged for immunocompromised patients who do not
respond to vaccines. Unfortunately, Omicron sublineages are resistant to monoclonal …