Development of cationic oligodiaminogalactoses specifically binding to duplex RNA, but not to duplex DNA

H Torigoe, S Nakayama, T Shiraishi, K Sato, RI Hara… - Thermochimica …, 2024 - Elsevier
Duplex RNA stabilization is important for the application in the artificial silencing of gene
expression. Excess usage of cationic molecules with low binding affinity to duplex RNA may …

[HTML][HTML] Exploring rigid-backbone protein docking in biologics discovery: a test using the DARPin scaffold

F Gaudreault, J Baardsnes, Y Martynova… - Frontiers in Molecular …, 2023 - ncbi.nlm.nih.gov
Accurate protein-protein docking remains challenging, especially for artificial biologics not
coevolved naturally against their protein targets, like antibodies and other engineered …