Detection and analysis of chiral molecules as disease biomarkers
The chirality of small metabolic molecules is important in controlling physiological processes
and indicating the health status of humans. Abnormal enantiomeric ratios of chiral molecules …
and indicating the health status of humans. Abnormal enantiomeric ratios of chiral molecules …
Promising application of D-amino acids toward clinical therapy
The versatile roles of D-amino acids (D-AAs) in foods, diseases, and organisms, etc., have
been widely reported. They have been regarded, not only as biomarkers of diseases but …
been widely reported. They have been regarded, not only as biomarkers of diseases but …
A D-cysteine desulfhydrase, SlDCD2, participates in tomato fruit ripening by modulating ROS homoeostasis and ethylene biosynthesis
YQ Zhao, KD Hu, GF Yao, SY Wang… - Horticulture …, 2023 - academic.oup.com
Hydrogen sulfide (H2S) is involved in multiple processes during plant growth and
development. D-cysteine desulfhydrase (DCD) can produce H2S with D-cysteine as the …
development. D-cysteine desulfhydrase (DCD) can produce H2S with D-cysteine as the …
d-Amino acids: new clinical pathways for brain diseases
IN de Oliveira Souza, R Roychaudhuri… - Trends in Molecular …, 2023 - cell.com
Free d-amino acids (d-AAs) are emerging as a novel and important class of signaling
molecules in many organs, including the brain and endocrine systems. There has been …
molecules in many organs, including the brain and endocrine systems. There has been …
d‐Amino acids in biological systems
S Du, M Wey, DW Armstrong - Chirality, 2023 - Wiley Online Library
Investigations on the occurrence and biochemical roles of free D‐amino acids and D‐amino
acid‐containing peptides and proteins in living systems have increased in frequency and …
acid‐containing peptides and proteins in living systems have increased in frequency and …
H2S-Generating Cytosolic L-Cysteine Desulfhydrase and Mitochondrial D-Cysteine Desulfhydrase from Sweet Pepper (Capsicum annuum L.) Are Regulated During …
MA Muñoz-Vargas, J López-Jaramillo… - Antioxidants & Redox …, 2023 - liebertpub.com
Aims: Pepper fruit is a horticultural product worldwide consumed that has great nutritional
and economic relevance. Besides the phenotypical changes that undergo pepper fruit …
and economic relevance. Besides the phenotypical changes that undergo pepper fruit …
Hydrogen sulfide and polysulfides induce GABA/glutamate/d-serine release, facilitate hippocampal LTP, and regulate behavioral hyperactivity
H Furuie, Y Kimura, T Akaishi, M Yamada… - Scientific reports, 2023 - nature.com
Hydrogen sulfide (H2S) and polysulfides (H2Sn, n≥ 2) are signaling molecules produced
by 3-mercaptopyruvate sulfurtransferase (3MST) that play various physiological roles …
by 3-mercaptopyruvate sulfurtransferase (3MST) that play various physiological roles …
L-cysteine methyl ester overcomes the deleterious effects of morphine on ventilatory parameters and arterial blood-gas chemistry in unanesthetized rats
We are developing a series of thiolesters that produce an immediate and sustained reversal
of the deleterious effects of opioids, such as morphine and fentanyl, on ventilation without …
of the deleterious effects of opioids, such as morphine and fentanyl, on ventilation without …
[HTML][HTML] The ventilatory depressant actions but not the antinociceptive effects of morphine are blunted in rats receiving intravenous infusion of L-cysteine ethyl ester
This study demonstrates that intravenous infusion of the cell-penetrant thiol ester, L-cysteine
ethyl ester (L-CYSee), to adult male Sprague-Dawley rats elicited (a) minor alterations in …
ethyl ester (L-CYSee), to adult male Sprague-Dawley rats elicited (a) minor alterations in …
Hydrogen Sulfide (H2S)/Polysulfides (H2Sn) Signalling and TRPA1 Channels Modification on Sulfur Metabolism
H Kimura - Biomolecules, 2024 - mdpi.com
Hydrogen sulfide (H2S) and polysulfides (H2Sn, n≥ 2) produced by enzymes play a role as
signalling molecules regulating neurotransmission, vascular tone, cytoprotection …
signalling molecules regulating neurotransmission, vascular tone, cytoprotection …