A substantial proportion of disease risk for common complex disorders is attributable to
environmental exposures and pollutants. An appreciation of how environmental pollutants …

There is a great deal of hype surrounding the concept of personalized medicine.
Personalized medicine is rooted in the belief that since individuals possess nuanced and …

Abstract tRNA-derived fragments (tRFs) are an emerging category of small non-coding
RNAs that are generated from cleavage of mature tRNAs or tRNA precursors. The advance …

Abstract tRNA-derived small RNAs (tsRNAs), including tRNA-derived fragments (tRFs) and
tRNA halves (tiRNAs), are small regulatory RNAs processed from mature tRNAs or …

The release of RNA-containing extracellular vesicles (EV) into the extracellular milieu has
been demonstrated in a multitude of different in vitro cell systems and in a variety of body …

Tumor-released RNA may mediate intercellular communication and serve as biomarkers.
Here we develop a protocol enabling quantitative, minimally biased analysis of extracellular …

The study of eukaryotic tRNA processing has given rise to an explosion of new information
and insights in the last several years. We now have unprecedented knowledge of each step …

Transfer RNA (tRNA) is present at tens of millions of transcripts in a human cell and is the
most abundant RNA in moles among all cellular RNAs. tRNA is also the most extensively …

Once deemed heretical, emerging evidence now supports the notion that the inheritance of
acquired characteristics can occur through ancestral exposures or experiences and that …

The biogenesis of the RNA payload of mature sperm is of great interest, because RNAs
delivered to the zygote at fertilization can affect early development. Here, we tested the …