Fucoxanthin: A promising compound for human inflammation-related diseases

M Liu, W Li, Y Chen, X Wan, J Wang - Life sciences, 2020 - Elsevier
Fucoxanthin, a natural product of carotenoids, is a potential drug source obtained from
marine algae. The special chemical structure of fucoxanthin has equipped it with a variety of …

Liver cancer: therapeutic challenges and the importance of experimental models

M Galicia-Moreno, JA Silva-Gomez… - Canadian Journal of …, 2021 - Wiley Online Library
Liver cancer is one of the main causes of death related to cancer worldwide; its etiology is
related with infections by C or B hepatitis virus, alcohol consumption, smoking, obesity …

[HTML][HTML] Standardized extract of ginger ameliorates liver cancer by reducing proliferation and inducing apoptosis through inhibition oxidative stress/inflammation …

AA Hamza, GH Heeba, S Hamza, A Abdalla… - Biomedicine & …, 2021 - Elsevier
Ginger has been proposed as quite a promising candidate for cancer prevention. The
purpose of this study was to assess the chemo-preventive effects of ginger. Furthermore, this …

Combining crocin and sorafenib improves their tumor-inhibiting effects in a rat model of diethylnitrosamine-induced cirrhotic-hepatocellular carcinoma

B Awad, AA Hamza, A Al-Maktoum, S Al-Salam, A Amin - Cancers, 2023 - mdpi.com
Simple Summary Liver cancer represents one of the most lethal forms of cancer, with
hepatocellular carcinoma (HCC) accounting for the majority of its incidences and deaths …

Therapeutic effects of crocin alone or in combination with sorafenib against hepatocellular carcinoma: in vivo & in vitro insights

S Abdu, N Juaid, A Amin, M Moulay, N Miled - Antioxidants, 2022 - mdpi.com
This study investigated the therapeutic effects of the phytochemical crocin alone or in
combination with sorafenib both in rats chemically induced with hepatocellular carcinoma …

Safranal prevents liver cancer through inhibiting oxidative stress and alleviating inflammation

Y Abdalla, A Abdalla, AA Hamza, A Amin - Frontiers in Pharmacology, 2022 - frontiersin.org
Despite all efforts, an effective and safe treatment for liver cancer remains elusive. Natural
products and their derived biomolecules are potential resources to mine for novel anti …

[PDF][PDF] Lipid remodeling in hepatocyte proliferation and hepatocellular carcinoma

Z Hall, D Chiarugi, E Charidemou, J Leslie, E Scott… - …, 2021 - Wiley Online Library
Background and Aims Hepatocytes undergo profound metabolic rewiring when primed to
proliferate during compensatory regeneration and in hepatocellular carcinoma (HCC) …

DeepACP: a novel computational approach for accurate identification of anticancer peptides by deep learning algorithm

L Yu, R Jing, F Liu, J Luo, Y Li - Molecular Therapy-Nucleic Acids, 2020 - cell.com
Cancer is one of the most dangerous diseases to human health. The accurate prediction of
anticancer peptides (ACPs) would be valuable for the development and design of novel …

Molecular characterization of the grape seeds extract's effect against chemically induced liver cancer: In vivo and in vitro analyses

AA Hamza, GH Heeba, HM Elwy, C Murali… - Scientific reports, 2018 - nature.com
The purpose of this study was to investigate the anti-cancer property of grape seed extract
(GSE) during early stages of developing liver cancer using a two-stage carcinogenic model …

Experimental models of hepatocellular carcinoma—a preclinical perspective

A Blidisel, I Marcovici, D Coricovac, F Hut… - Cancers, 2021 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is characterized by a broad molecular
and genetic heterogeneity, which makes it a challenging subject in terms of the underlying …