Genomic architecture of autism from comprehensive whole-genome sequence annotation
B Trost, B Thiruvahindrapuram, AJS Chan… - Cell, 2022 - cell.com
Fully understanding autism spectrum disorder (ASD) genetics requires whole-genome
sequencing (WGS). We present the latest release of the Autism Speaks MSSNG resource …
sequencing (WGS). We present the latest release of the Autism Speaks MSSNG resource …
Genomic insights into the formation of human populations in East Asia
The deep population history of East Asia remains poorly understood owing to a lack of
ancient DNA data and sparse sampling of present-day people,. Here we report genome …
ancient DNA data and sparse sampling of present-day people,. Here we report genome …
Large-scale migration into Britain during the Middle to Late Bronze Age
Present-day people from England and Wales have more ancestry derived from early
European farmers (EEF) than did people of the Early Bronze Age 1. To understand this, here …
European farmers (EEF) than did people of the Early Bronze Age 1. To understand this, here …
Palaeogenomics of upper palaeolithic to neolithic European hunter-gatherers
Modern humans have populated Europe for more than 45,000 years,. Our knowledge of the
genetic relatedness and structure of ancient hunter-gatherers is however limited, owing to …
genetic relatedness and structure of ancient hunter-gatherers is however limited, owing to …
High-depth African genomes inform human migration and health
The African continent is regarded as the cradle of modern humans and African genomes
contain more genetic variation than those from any other continent, yet only a fraction of the …
contain more genetic variation than those from any other continent, yet only a fraction of the …
Elevated genetic risk for multiple sclerosis emerged in steppe pastoralist populations
Multiple sclerosis (MS) is a neuro-inflammatory and neurodegenerative disease that is most
prevalent in Northern Europe. Although it is known that inherited risk for MS is located within …
prevalent in Northern Europe. Although it is known that inherited risk for MS is located within …
The genetic history of the Southern Arc: A bridge between West Asia and Europe
By sequencing 727 ancient individuals from the Southern Arc (Anatolia and its neighbors in
Southeastern Europe and West Asia) over 10,000 years, we contextualize its Chalcolithic …
Southeastern Europe and West Asia) over 10,000 years, we contextualize its Chalcolithic …
The landscape of mtDNA modifications in cancer: a tale of two cities
KL Hertweck, S Dasgupta - Frontiers in oncology, 2017 - frontiersin.org
Mitochondria from normal and cancerous cells represent a tale of two cities, wherein both
execute similar processes but with different cellular and molecular effects. Given the number …
execute similar processes but with different cellular and molecular effects. Given the number …
The genomic history of the Iberian Peninsula over the past 8000 years
We assembled genome-wide data from 271 ancient Iberians, of whom 176 are from the
largely unsampled period after 2000 BCE, thereby providing a high-resolution time transect …
largely unsampled period after 2000 BCE, thereby providing a high-resolution time transect …
A high-resolution picture of kinship practices in an Early Neolithic tomb
To explore kinship practices at chambered tombs in Early Neolithic Britain, here we
combined archaeological and genetic analyses of 35 individuals who lived about 5,700 …
combined archaeological and genetic analyses of 35 individuals who lived about 5,700 …