Pre-eclampsia

E Dimitriadis, DL Rolnik, W Zhou… - Nature reviews Disease …, 2023 - nature.com
Pre-eclampsia is a life-threatening disease of pregnancy unique to humans and a leading
cause of maternal and neonatal morbidity and mortality. Women who survive pre-eclampsia …

Preeclampsia

LA Magee, KH Nicolaides… - New England Journal of …, 2022 - Mass Medical Soc
Preeclampsia Preeclampsia complicates 2 to 4% of all pregnancies and accounts for about
46,000 maternal deaths and 500,000 fetal or newborn deaths each year. Antihypertensive …

Cell-free DNA methylome analysis for early preeclampsia prediction

M De Borre, H Che, Q Yu, L Lannoo, K De Ridder… - Nature Medicine, 2023 - nature.com
Preeclampsia (PE) is a leading cause for peripartal morbidity, especially if developing early
in gestation. To enable prophylaxis in the prevention of PE, pregnancies at risk of PE must …

Pravastatin versus placebo in pregnancies at high risk of term preeclampsia

M Döbert, AN Varouxaki, AC Mu, A Syngelaki… - Circulation, 2021 - Am Heart Assoc
Background: Effective screening for term preeclampsia is provided by a combination of
maternal factors with measurements of mean arterial pressure, serum placental growth …

Prevention, diagnosis, and management of hypertensive disorders of pregnancy: a comparison of international guidelines

RG Sinkey, AN Battarbee, NA Bello, CW Ives… - Current hypertension …, 2020 - Springer
Abstract Purpose of Review Hypertensive disorders of pregnancy (HDP)—gestational
hypertension, preeclampsia, and eclampsia—are a leading cause of adverse maternal and …

Calcium for pre‐eclampsia prevention: a systematic review and network meta‐analysis to guide personalised antenatal care

ML Woo Kinshella, C Sarr, A Sandhu… - … Journal of Obstetrics …, 2022 - Wiley Online Library
Background Calcium supplementation reduces the risk of pre‐eclampsia, but questions
remain about the dosage to prescribe and who would benefit most. Objectives To evaluate …

Early prediction of preeclampsia via machine learning

I Marić, A Tsur, N Aghaeepour, A Montanari… - American Journal of …, 2020 - Elsevier
Background Early prediction of preeclampsia is challenging because of poorly understood
causes, various risk factors, and likely multiple pathogenic phenotypes of preeclampsia …

New advances in prediction and surveillance of preeclampsia: role of machine learning approaches and remote monitoring

M Hackelöer, L Schmidt, S Verlohren - Archives of gynecology and …, 2023 - Springer
Preeclampsia, a multisystem disorder in pregnancy, is still one of the main causes of
maternal morbidity and mortality. Due to a lack of a causative therapy, an accurate prediction …

Early prediction and longitudinal modeling of preeclampsia from multiomics

I Marić, K Contrepois, MN Moufarrej, IA Stelzer… - Patterns, 2022 - cell.com
Preeclampsia is a complex disease of pregnancy whose physiopathology remains unclear.
We developed machine-learning models for early prediction of preeclampsia (first 16 weeks …

Cardiovascular events following pregnancy complicated by pre‐eclampsia with emphasis on comparison between early‐and late‐onset forms: systematic review and …

A Dall'Asta, F D'Antonio, G Saccone… - … in Obstetrics & …, 2021 - Wiley Online Library
Objective To elucidate whether pre‐eclampsia (PE) and the gestational age at onset of the
disease (early‐vs late‐onset PE) have an impact on the risk of long‐term maternal …