A radiopharmaceutical [89Zr] Zr-DFO-nimotuzumab for immunoPET with epidermal growth factor receptor expression in vivo

Y Tang, Y Hu, W Liu, L Chen, Y Zhao, H Ma… - Nuclear Medicine and …, 2019 - Elsevier
Introduction The potential of the positron-emitting zirconium-89 (89 Zr)(t 1/2= 78.4 h) has
been recently reported for immune positron emission tomography (immunoPET) …

Immuno-PET imaging and pharmacokinetics of an anti-CEA scFv-based trimerbody and its monomeric counterpart in human gastric carcinoma-bearing mice

X Rios, M Compte, V Gómez-Vallejo… - Molecular …, 2019 - ACS Publications
Monoclonal antibodies (mAbs) are currently used as therapeutic agents in different types of
cancer. However, mAbs and antibody fragments developed so far show suboptimal …

Safety assessment, radioiodination and preclinical evaluation of antinuclear antibody as novel medication for prostate cancer in mouse xenograft model

TMC Nguyen, LDC Hoang, TKG Nguyen… - Scientific Reports, 2023 - nature.com
This study aims to provide in vitro and in vivo data to support the utilization of antinuclear
antibodies (ANAs) as novel tools for the diagnosis and treatment of prostate cancers. The …

Nimotuzumab iodine-131 conjugated with MnFe2O4 for potential dual-modality (MRI/SPECT) imaging nanoprobe

AR Putra, Y Yulizar, R Ritawidya… - Materials Science and …, 2022 - Elsevier
Manganese ferrite nanoparticle (MnFe 2 O 4 NPs) has introduced a versatile platform to
develop a multifunctional nanosystem for Magnetic Resonance Imaging (MRI) and Single …

Nimotuzumab combined with concurrent chemoradiotherapy benefits patients with advanced nasopharyngeal carcinoma

Z Li, Y Li, S Yan, J Fu, Q Zhou, X Huang… - OncoTargets and …, 2017 - Taylor & Francis
Background The potential benefits and possible risks associated with combined
nimotuzumab and concurrent chemoradiotherapy in patients with advanced …

Biodistribution and Tumor Uptake of 67Ga-Nimotuzumab in a Malignant Pleural Mesothelioma Xenograft

V Izquierdo-Sánchez, S Muñiz-Hernández… - Molecules, 2018 - mdpi.com
Malignant pleural mesothelioma (MPM) is the most common tumor of the pulmonary pleura.
It is a rare and aggressive malignancy, generally associated with continuous occupational …

Efficacy of nimotuzumab (hR3) conjugated with 131I or 90Y in laryngeal carcinoma xenograft mouse model

TT Nguyen, AS Ho, TKG Nguyen… - … Journal of Radiation …, 2021 - Taylor & Francis
Purpose The humanized monoclonal antibody hR3, both alone and in combination with
other chemotherapeutic agents and radiotherapy, can be used to treat head and neck …

Preliminary in vitro comparison of 111In and 131I labeled nimotuzumabs

Z Liao, F Li, Y Tang, W Liu, J Gao, T Lan, J Yang… - … of Radioanalytical and …, 2021 - Springer
The anti-tumor cell proliferative effect of [111 In] In-DOTA-nimotuzumab and [131 I] I-ATE-
nimotuzumab was systematically investigated. Both indium-111 and iodine-131 were …

Antinuclear Antibodies: Safety Assessments, Radioiodination and Preclinical Evaluations in Pc3 Xenograft Mice

TT Nguyen, TMC Nguyen, LDC Hoang, QC Nguyen… - 2023 - researchsquare.com
This study aims to provide in vitro and in vivo data to support the utilization of antinuclear
antibodies (ANAs) as novel tools for the diagnosis and treatment of prostate cancers. The …

Principle and Applications of Immunodiagnostics Using Radioisotope as Tracers

SK Suman, R Sharma, C Kumar - … from Laboratory to Point-Of-Care …, 2021 - Springer
The tremendous improvement in the field of production of radioisotopes and monoclonal
antibody and advance instrumentation have revolutionized the use of radioisotope in the …