The Potential Role of Voltage‐Dependent Anion Channel in the Treatment of Parkinson's Disease

Y He, W Wang, T Yang, ER Thomas… - … Medicine and Cellular …, 2022 - Wiley Online Library
Parkinson's disease (PD) is a neurodegenerative disease second only to Alzheimer's
disease in terms of prevalence. Previous studies have indicated that the occurrence and …

Tremendous fidelity of vitamin D3 in age-related neurological disorders

M Skv, SM Abraham, O Eshwari, K Golla… - Molecular …, 2024 - Springer
Vitamin D3 (VD) is a secosteroid hormone and shows a pleiotropic effect in brain-related
disorders where it regulates redox imbalance, inflammation, apoptosis, energy production …

Vitamin D (VD3) intensifies the effects of exercise and prevents alterations of behavior, brain oxidative stress, and neuroinflammation, in hemiparkinsonian rats

RO Da Costa, CVJ Gadelha-Filho… - Neurochemical …, 2023 - Springer
In the present study, we investigated the effects of physical exercise in the presence of
Vitamin D3 (VD3), on 6-hydroxydopamine (6-OHDA)-lesioned hemiparkinsonian rats. The …

Risk of Parkinson's disease in multiple sclerosis and neuromyelitis optica spectrum disorder: a nationwide cohort study in South Korea

S Kwon, SY Jung, JH Jung, Y Yeo, EB Cho… - Journal of Neurology …, 2022 - jnnp.bmj.com
Background Neurodegeneration is associated with pathogenesis of both multiple sclerosis
(MS) and neuromyelitis optica (NMOSD). Parkinson's disease (PD) is a representative …

Neuroprotective and therapeutic effects of calcitriol in rotenone-induced Parkinson's disease rat model

A Magdy, EAE Farrag, SM Hamed… - Frontiers in Cellular …, 2022 - frontiersin.org
Parkinson's disease (PD) is the second most common neurodegenerative disease.
Treatment of PD is challenging, as current treatment strategies are only symptomatic and do …

Vitamin D3 actions on astrocyte cells: A target for therapeutic strategy in Parkinson's disease?

EA de Siqueira, EP Magalhães, TL Sampaio… - Neuroscience …, 2023 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disease characterized by the loss of
dopaminergic cells in the substantia nigra pars compacta. PD patients' brains show …

Resveratrol and 1, 25-dihydroxyvitamin D decrease Lingo-1 levels, and improve behavior in harmaline-induced Essential tremor, suggesting potential therapeutic …

Z Pirmoradi, M Nakhaie, H Ranjbar… - Scientific Reports, 2024 - nature.com
Essential tremor (ET) is a neurological disease that impairs motor and cognitive functioning.
A variant of the Lingo-1 genetic locus is associated with a heightened ET risk, and increased …

Conservative management of acute sports-related concussions: a narrative review

S Kureshi, M Mendizabal, J Francis, HR Djalilian - Healthcare, 2024 - mdpi.com
This review explores the application of the conservative management model for pain to
sports-related concussions (SRCs), framing concussions as a distinct form of pain syndrome …

Selenium nanoparticles decorated with polysaccharides from Sargassum fusiforme protects against 6-OHDA-induced neurotoxicity in PC12 cells and rat model of …

H Zhao, J Song, T Wang, X Fan - Nanomedicine: Nanotechnology, Biology …, 2024 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disorder and identifying disease-causing
pathways and drugs that target them has remained challenging. Herein, selenium …

Calcitriol restrains microglial M1 polarization and alleviates dopaminergic degeneration in hemiparkinsonian mice by boosting regulatory T‐cell expansion

Y Xie, L Chen, J Chen, Y Chen - Brain and Behavior, 2024 - Wiley Online Library
Objective Vitamin D deficiency is a risk factor for Parkinson's disease (PD) and vitamin D
supplementation robustly alleviates neurodegeneration in PD models. However, the …