Virulence factors in carbapenem-resistant hypervirulent Klebsiella pneumoniae

G Mendes, ML Santos, JF Ramalho, A Duarte… - Frontiers in …, 2023 - frontiersin.org
Hypervirulence and carbapenem-resistant have emerged as two distinct evolutionary
pathotypes of Klebsiella pneumoniae, with both reaching their epidemic success and posing …

Carbapenem-resistant Klebsiella pneumoniae: the role of plasmids in emergence, dissemination, and evolution of a major clinical challenge

V Di Pilato, S Pollini, V Miriagou… - Expert Review of Anti …, 2024 - Taylor & Francis
Introduction Klebsiella pneumoniae is a major agent of healthcare-associated infections and
a cause of some community-acquired infections, including severe bacteremic infections …

Mortality attributable to bloodstream infections caused by different carbapenem-resistant gram-negative bacilli: results from a nationwide study in Italy (ALARICO …

M Falcone, G Tiseo, S Carbonara… - Clinical Infectious …, 2023 - academic.oup.com
Background Our aim was to analyze mortality attributable to carbapenem-resistant (CR)
gram-negative bacilli (GNB) in patients with bloodstream infections (BSIs). Methods …

[HTML][HTML] Emergence and persistent spread of carbapenemase-producing Klebsiella pneumoniae high-risk clones in Greek hospitals, 2013 to 2022

K Tryfinopoulou, M Linkevicius, O Pappa… - …, 2023 - eurosurveillance.org
Background Preliminary unpublished results of the survey of carbapenem-and/or colistin-
resistant Enterobacterales (CCRE survey) showed the expansion of carbapenemase …

Non-antibiotic compounds associated with humans and the environment can promote horizontal transfer of antimicrobial resistance genes

I Alav, MMC Buckner - Critical Reviews in Microbiology, 2023 - Taylor & Francis
Horizontal gene transfer plays a key role in the global dissemination of antimicrobial
resistance (AMR). AMR genes are often carried on self-transmissible plasmids, which are …

Genetic plurality of blaKPC-2-harboring plasmids in high-risk clones of Klebsiella pneumoniae of environmental origin

JPR Furlan, R da Silva Rosa, MS Ramos… - Science of The Total …, 2023 - Elsevier
International high-risk clones of Klebsiella pneumoniae are important human pathogens that
are spreading to the environment. In the COVID-19 pandemic scenario, the frequency of …

Occurrence of Klebsiella pneumoniae ST244 and ST11 extensively drug-resistant producing KPC, NDM, OXA-370 in wastewater, Brazil

K Montenegro, C Flores… - Journal of Applied …, 2023 - academic.oup.com
Aims To investigate the occurrence of carbapenem-resistant Klebsiella pneumoniae (CRKP)
and their clonal relationships from hospital and municipal wastewater treatment plants …

Hypervirulent Klebsiella pneumoniae : An update on epidemiology, detection and antibiotic resistance

B Kocsis - Acta Microbiologica et Immunologica Hungarica, 2023 - akjournals.com
Klebsiella pneumoniae is a major human pathogen as it is responsible for various infections.
In the past years hypervirulent K. pneumoniae (hvKP) emerged and disseminated …

Early detection of OXA-232-producing Klebsiella pneumoniae in China predating its global emergence

H Heng, X Yang, H Zhang, R Sun, L Ye, J Li… - Microbiological …, 2024 - Elsevier
Antibiotic resistance is a global health issue, with Klebsiella pneumoniae (KP) posing a
particular threat due to its ability to acquire resistance to multiple drug classes rapidly. OXA …

Molecular characterization of the convergent carbapenem-resistant and hypervirulent Klebsiella pneumoniae strain K1-ST23, collected in Chile during the COVID-19 …

F Morales-León, M Matus-Köhler… - Microbiology …, 2023 - Am Soc Microbiol
The aim of this study was to investigate the genomic features of a carbapenem-resistant
hypervirulent Klebsiella pneumoniae (CR-hvKp) isolate (K-2157) collected in Chile …