Comparative efficacy and tolerability of 32 oral and long-acting injectable antipsychotics for the maintenance treatment of adults with schizophrenia: a systematic …

J Schneider-Thoma, K Chalkou, C Dörries, I Bighelli… - The lancet, 2022 - thelancet.com
Background Schizophrenia is a common, severe, and usually chronic disorder. Maintenance
treatment with antipsychotic drugs can prevent relapse but also causes side-effects. We …

Systematic literature review of schizophrenia clinical practice guidelines on acute and maintenance management with antipsychotics

CU Correll, A Martin, C Patel, C Benson, R Goulding… - Schizophrenia, 2022 - nature.com
Clinical practice guidelines (CPGs) translate evidence into recommendations to improve
patient care and outcomes. To provide an overview of schizophrenia CPGs, we conducted a …

Long-acting injectable versus oral antipsychotics for the maintenance treatment of schizophrenia: a systematic review and comparative meta-analysis of randomised …

T Kishimoto, K Hagi, S Kurokawa, JM Kane… - The Lancet …, 2021 - thelancet.com
Background Evidence of comparative benefits of long-acting injectable antipsychotics (LAIs)
versus oral antipsychotics for schizophrenia has been inconsistent across study designs …

Real-world effectiveness of long-acting injectable antipsychotic treatments in a nationwide cohort of 12,373 patients with schizophrenia-spectrum disorders

L Boyer, B Falissard, P Nuss, C Collin, S Duret… - Molecular …, 2023 - nature.com
This mirror-image study aimed to evaluate the real-life effectiveness of long-acting injectable
antipsychotics (LAI) in schizophrenia. Patients with schizophrenia initiating LAIs January …

Controversies surrounding the use of long-acting injectable antipsychotic medications for the treatment of patients with schizophrenia

JM Kane, JP McEvoy, CU Correll, PM Llorca - CNS drugs, 2021 - Springer
Schizophrenia is a serious mental illness that requires continuous and effective long-term
management to reduce symptoms, improve quality of life, and prevent relapse. Oral …

Comparison of long-acting injectable antipsychotics with oral antipsychotics and suicide and all-cause mortality in patients with newly diagnosed schizophrenia

CY Huang, SC Fang, YHJ Shao - JAMA network open, 2021 - jamanetwork.com
Importance Schizophrenia is generally considered to be among the most severe psychiatric
disorders because of the excessive mortality associated with it. Research to find means to …

Long-term continuity of antipsychotic treatment for schizophrenia: a nationwide study

JM Rubio, H Taipale, A Tanskanen… - Schizophrenia …, 2021 - academic.oup.com
Schizophrenia often requires long-term treatment with antipsychotic medication. This study
aims to measure the continuity of antipsychotic treatment over the course of illness in …

[HTML][HTML] Advances in long-acting slow effective release antiretroviral therapies for treatment and prevention of HIV infection

MU Nayan, B Sillman, M Hasan, S Deodhar… - Advanced Drug Delivery …, 2023 - Elsevier
Adherence to daily oral antiretroviral therapy (ART) is a barrier to both treatment and
prevention of human immunodeficiency virus (HIV) infection. To overcome limitations of life …

Efficacy of oral versus long-acting antipsychotic treatment in patients with early-phase schizophrenia in Europe and Israel: a large-scale, open-label, randomised trial …

I Winter-van Rossum, M Weiser, S Galderisi… - The Lancet …, 2023 - thelancet.com
Background Schizophrenia is a severe psychiatric disorder with periods of remission and
relapse. As discontinuation of antipsychotic medication is the most important reason for …

Association of long-acting injectable antipsychotics and oral antipsychotics with disease relapse, health care use, and adverse events among people with …

Y Wei, VKC Yan, W Kang, ICK Wong… - JAMA network …, 2022 - jamanetwork.com
Importance Evidence for improved clinical outcomes with long-acting injectable
antipsychotics (LAIAs) vs oral antipsychotics (OAs) is limited in Asian populations and …