Pancreatic cancer and the FAMMM syndrome
HT Lynch, RM Fusaro, JF Lynch, R Brand - Familial cancer, 2008 - Springer
Hereditary cancer syndromes provide excellent models for molecular genetic studies that
may aid significantly in case detection, surveillance, and management. Ultimately …
may aid significantly in case detection, surveillance, and management. Ultimately …
Natural products and their analogues as efficient anticancer drugs
S Coseri - Mini reviews in medicinal chemistry, 2009 - ingentaconnect.com
Every year about 7 million people die from of various types of cancer, making this disease
responsible for 12.5% of deaths worldwide. Consequently, there is an overwhelming …
responsible for 12.5% of deaths worldwide. Consequently, there is an overwhelming …
[HTML][HTML] Vascular endothelial growth factor (VEGF) and its role in non-endothelial cells: autocrine signalling by VEGF
AM Duffy, DJ Bouchier-Hayes… - Madame Curie …, 2013 - ncbi.nlm.nih.gov
Vascular endothelial growth factor (VEGF) is a potent angiogenic factor and was first
described as an essential growth factor for vascular endothelial cells. VEGF is up-regulated …
described as an essential growth factor for vascular endothelial cells. VEGF is up-regulated …
Immortal human pancreatic duct epithelial cell lines with near normal genotype and phenotype
H Ouyang, L Mou, C Luk, N Liu, J Karaskova… - The American journal of …, 2000 - Elsevier
Immortal epithelial cell lines were previously established after transduction of the HPV16-
E6E7 genes into primary cultures of normal pancreatic duct epithelial cells. Single clones …
E6E7 genes into primary cultures of normal pancreatic duct epithelial cells. Single clones …
Role of EUS in the preoperative staging of pancreatic cancer: a large single-center experience
FG Gress, RH Hawes, TJ Savides, SO Ikenberry… - Gastrointestinal …, 1999 - Elsevier
Background: Current methods for staging pancreatic cancer can be inaccurate, invasive,
and expensive. Endoscopic ultrasound (EUS) is reported to be highly accurate for local …
and expensive. Endoscopic ultrasound (EUS) is reported to be highly accurate for local …
Amplification and overexpression of the AKT2 oncogene in a subset of human pancreatic ductal adenocarcinomas
BA Ruggeri, L Huang, M Wood… - … in cooperation with …, 1998 - Wiley Online Library
AKT2, an oncogene encoding a protein serine‐threonine kinase implicated in
phosphatidylinositol‐3‐OH kinase signaling, is amplified in some human ovarian and …
phosphatidylinositol‐3‐OH kinase signaling, is amplified in some human ovarian and …
Expression and in‐situ localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer
TM Gress, F Müller‐Pillasch, MM Lerch… - … journal of cancer, 1995 - Wiley Online Library
Pancreatic cancer shows a strong desmoplastic reaction characterized by a remarkable
proliferation of interstitial connective tissue (collagens type I and III, fibronectin). In this study …
proliferation of interstitial connective tissue (collagens type I and III, fibronectin). In this study …
Neurotrophins and Trk receptors in human pancreatic ductal adenocarcinoma: Expression patterns and effects on In vitro invasive behavior
SJ Miknyoczki, D Lang, L Huang… - … journal of cancer, 1999 - Wiley Online Library
The aggressive and highly metastatic behavior observed in pancreatic ductal
adenocarcinoma (PDAC) may be due to autocrine and/or paracrine interactions …
adenocarcinoma (PDAC) may be due to autocrine and/or paracrine interactions …
De novo expression of vascular endothelial growth factor in human pancreatic cancer: evidence for an autocrine mitogenic loop
Z Von Marschall, T Cramer, M Höcker, R Burde, T Plath… - Gastroenterology, 2000 - Elsevier
Background & Aims: The role of vascular endothelial growth factor (VEGF) and its receptors
in tumor angiogenesis has been well established. We analyzed the expression pattern and …
in tumor angiogenesis has been well established. We analyzed the expression pattern and …
Identification of potential markers for the detection of pancreatic cancer through comparative serum protein expression profiling
M Ehmann, K Felix, D Hartmann, M Schnölzer… - Pancreas, 2007 - journals.lww.com
Objective: Early detection is the only promising approach to significantly improve the survival
of patients with pancreatic cancer (PCa). Noninvasive tools for the diagnosis, prognosis, and …
of patients with pancreatic cancer (PCa). Noninvasive tools for the diagnosis, prognosis, and …