Hereditary cancer syndromes provide excellent models for molecular genetic studies that
may aid significantly in case detection, surveillance, and management. Ultimately …

Every year about 7 million people die from of various types of cancer, making this disease
responsible for 12.5% of deaths worldwide. Consequently, there is an overwhelming …

Vascular endothelial growth factor (VEGF) is a potent angiogenic factor and was first
described as an essential growth factor for vascular endothelial cells. VEGF is up-regulated …

Immortal epithelial cell lines were previously established after transduction of the HPV16-
E6E7 genes into primary cultures of normal pancreatic duct epithelial cells. Single clones …

Background: Current methods for staging pancreatic cancer can be inaccurate, invasive,
and expensive. Endoscopic ultrasound (EUS) is reported to be highly accurate for local …

AKT2, an oncogene encoding a protein serine‐threonine kinase implicated in
phosphatidylinositol‐3‐OH kinase signaling, is amplified in some human ovarian and …

Pancreatic cancer shows a strong desmoplastic reaction characterized by a remarkable
proliferation of interstitial connective tissue (collagens type I and III, fibronectin). In this study …

The aggressive and highly metastatic behavior observed in pancreatic ductal
adenocarcinoma (PDAC) may be due to autocrine and/or paracrine interactions …

Background & Aims: The role of vascular endothelial growth factor (VEGF) and its receptors
in tumor angiogenesis has been well established. We analyzed the expression pattern and …

Objective: Early detection is the only promising approach to significantly improve the survival
of patients with pancreatic cancer (PCa). Noninvasive tools for the diagnosis, prognosis, and …