Biological activity of ionic liquids and their application in pharmaceutics and medicine
KS Egorova, EG Gordeev, VP Ananikov - Chemical reviews, 2017 - ACS Publications
Ionic liquids are remarkable chemical compounds, which find applications in many areas of
modern science. Because of their highly tunable nature and exceptional properties, ionic …
modern science. Because of their highly tunable nature and exceptional properties, ionic …
[HTML][HTML] Mammalian transient receptor potential TRPA1 channels: from structure to disease
K Talavera, JB Startek, J Alvarez-Collazo… - Physiological …, 2020 - journals.physiology.org
The transient receptor potential ankyrin (TRPA) channels are Ca 2+-permeable nonselective
cation channels remarkably conserved through the animal kingdom. Mammals have only …
cation channels remarkably conserved through the animal kingdom. Mammals have only …
Regulation of pain and itch by TRP channels
Nociception is an important physiological process that detects harmful signals and results in
pain perception. In this review, we discuss important experimental evidence involving some …
pain perception. In this review, we discuss important experimental evidence involving some …
Pharmacological effects of cannabidiol by transient receptor potential channels
L Etemad, G Karimi, MS Alavi, A Roohbakhsh - Life Sciences, 2022 - Elsevier
Cannabidiol (CBD), as a major phytocannabinoid of Cannabis sativa, has emerged as a
promising natural compound in the treatment of diseases. Its diverse pharmacological …
promising natural compound in the treatment of diseases. Its diverse pharmacological …
Involvement of Opioid System and TRPM8/TRPA1 Channels in the Antinociceptive Effect of Spirulina platensis
MA Freitas, A Vasconcelos, ECD Gonçalves… - Biomolecules, 2021 - mdpi.com
Spirulina platensis is a “super-food” and has attracted researchers' attention due to its anti-
inflammatory, antioxidant, and analgesic properties. Herein, we investigated the …
inflammatory, antioxidant, and analgesic properties. Herein, we investigated the …
Sensory TRP channels in three dimensions
MM Diver, JV Lin King, D Julius… - Annual review of …, 2022 - annualreviews.org
Transient receptor potential (TRP) ion channels are sophisticated signaling machines that
detect a wide variety of environmental and physiological signals. Every cell in the body …
detect a wide variety of environmental and physiological signals. Every cell in the body …
Axonal transport of late endosomes and amphisomes is selectively modulated by local Ca2+ efflux and disrupted by PSEN1 loss of function
PPY Lie, L Yoo, CN Goulbourne, MJ Berg… - Science …, 2022 - science.org
Dysfunction and mistrafficking of organelles in autophagy-and endosomal-lysosomal
pathways are implicated in neurodegenerative diseases. Here, we reveal selective …
pathways are implicated in neurodegenerative diseases. Here, we reveal selective …
Crystal structure of the epithelial calcium channel TRPV6
Precise regulation of calcium homeostasis is essential for many physiological functions. The
Ca2+-selective transient receptor potential (TRP) channels TRPV5 and TRPV6 play vital …
Ca2+-selective transient receptor potential (TRP) channels TRPV5 and TRPV6 play vital …
Nanoparticles-mediated ion channels manipulation: From their membrane interactions to bioapplications
Q Huang, W Zhu, X Gao, X Liu, Z Zhang… - Advanced Drug Delivery …, 2023 - Elsevier
Ion channels are transmembrane proteins ubiquitously expressed in all cells that control
various ions (eg Na+, K+, Ca 2+ and Cl-etc) crossing cellular plasma membrane, which play …
various ions (eg Na+, K+, Ca 2+ and Cl-etc) crossing cellular plasma membrane, which play …
TRP channels role in pain associated with neurodegenerative diseases
M Duitama, V Vargas-López, Z Casas… - Frontiers in …, 2020 - frontiersin.org
Transient receptor potential (TRP) are cation channels expressed in both non-excitable and
excitable cells from diverse tissues, including heart, lung, and brain. The TRP channel family …
excitable cells from diverse tissues, including heart, lung, and brain. The TRP channel family …