The no-reflow phenomenon relates to the inability to reperfuse regions of the myocardium
after ischemia, despite removal of the large epicardial coronary artery occlusion. The …

Vascular endothelial cells line the inner surface of the entire cardiovascular system as a
single layer and are involved in an impressive array of functions, ranging from the regulation …

Acute myocardial ischemia/reperfusion (I/R) injury is a significant, unsolved clinical puzzle.
In the disease context of acute myocardial infarction, reperfusion remains the only effective …

The formation of new blood vessels after myocardial infarction (MI) is essential for the
survival of existing and regenerated cardiac tissue. However, the extent of endogenous …

Despite prompt epicardial recanalization in patients presenting with ST-segment elevation
myocardial infarction (STEMI), coronary microvascular obstruction and dysfunction (CMVO) …

Aims We investigated the incidence and sequelae of angiographically visible distal
embolization (AVDE) after primary percutaneous coronary intervention (PCI) in ST-elevation …

Mitochondria are essential signaling organelles that regulate a broad range of cellular
processes and thereby heart function. Multiple mechanisms participate in the …

Primary percutaneous coronary intervention (PPCI) is the preferred reperfusion strategy for
treating acute ST-segment elevation myocardial infarction (STEMI). The main goals are to …

Myocardial infarction (MI) is the most common cause of heart failure (HF), the leading cause
of death in the developed world. Oxidative stress due to excessive production of reactive …

Ex situ heart perfusion (ESHP) was developed to preserve and evaluate donated hearts in a
perfused beating state. However, myocardial function declines during ESHP, which limits the …