The spectrum of post-myocardial infarction care: From acute ischemia to heart failure

KH Akhtar, MS Khan, SJ Baron, S Zieroth… - Progress in …, 2024 - Elsevier
Heart failure (HF) is the leading cause of mortality in patients with acute myocardial
infarction (AMI), with incidence ranging from 14% to 36% in patients admitted due to AMI. HF …

Regulatory pathways governing murine coronary vessel formation are dysregulated in the injured adult heart

S Payne, M Gunadasa-Rohling, A Neal… - Nature …, 2019 - nature.com
The survival of ischaemic cardiomyocytes after myocardial infarction (MI) depends on the
formation of new blood vessels. However, endogenous neovascularization is inefficient and …

Ischemic postconditioning: mechanisms, comorbidities, and clinical application

B Buchholz, M Donato, V D'Annunzio… - Molecular and cellular …, 2014 - Springer
Since ischemic heart disease (IHD) is a major cause of mortality and heart failure, novel
therapeutic strategies are expected to improve the clinical outcomes of patients with acute …

Balance of nitric oxide and reactive oxygen species in myocardial reperfusion injury and protection

A Folino, G Losano, R Rastaldo - Journal of cardiovascular …, 2013 - journals.lww.com
Depending on their concentrations, both nitric oxide (NO) and reactive oxygen species
(ROS) take part either in myocardial ischemia reperfusion injury or in protection by ischemic …

Intestinal ischemia-reperfusion leads to early systemic micro-rheological and multiorgan microcirculatory alterations in the rat

A Mester, Z Magyar, V Sogor, B Tanczos… - Clinical …, 2018 - content.iospress.com
BACKGROUND: Intestinal ischemia-reperfusion (I/R) is a potentially life-threatening
situation and its pathomechanism is not fully understood yet. OBJECTIVE: To investigate the …

Ultrasound-targeted microbubble cavitation with sodium nitrite synergistically enhances nitric oxide production and microvascular perfusion

ZY Gary, F Istvanic, X Chen, M Nouraie, S Shiva… - Ultrasound in medicine …, 2020 - Elsevier
Microvascular obstruction is a common repercussion of percutaneous coronary intervention
for distal microembolization, ischemia–reperfusion injury and inflammation, which increases …

Telmisartan protects against microvascular dysfunction during myocardial ischemia/reperfusion injury by activation of peroxisome proliferator-activated receptor …

XC Zeng, XS Li, H Wen - BMC cardiovascular disorders, 2013 - Springer
Background We investigated the potential of telmisartan to improve microvascular
dysfunction induced by myocardial ischemia/reperfusion (I/R) injury by activating the …

Measuring water distribution in the heart: preventing edema reduces ischemia–reperfusion injury

M Andrés‐Villarreal, I Barba, M Poncelas… - Journal of the …, 2016 - Am Heart Assoc
Background Edema is present in many heart diseases, and differentiation between
intracellular (ICW) and extracellular (ECW) myocardial water compartments would be …

Prospects for improving neovascularization of the ischemic heart: Lessons from development

N Smart - Microcirculation, 2017 - Wiley Online Library
Neovascularization of the ischemic myocardium postinfarction is necessary to restore blood
flow to vulnerable cardiomyocytes and will be indispensable for prospective regenerative …

[HTML][HTML] The role of von Willebrand factor and ADAMTS13 in the no-reflow phenomenon after primary percutaneous coronary intervention

B Zhao, J Li, X Luo, Q Zhou, H Chen… - Texas Heart Institute …, 2011 - ncbi.nlm.nih.gov
We prospectively studied the correlations between plasma levels of von Willebrand factor
and its cleaving protease—a disintegrin and metalloproteinase with thrombospondin type I …