Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

The diverse collection of microorganisms that inhabit the gastrointestinal tract, collectively
called the gut microbiota, profoundly influences many aspects of host physiology, including …

The blood-brain barrier (BBB) plays a vital role in regulating the trafficking of fluid, solutes
and cells at the blood-brain interface and maintaining the homeostatic microenvironment of …

Alzheimer's disease (AD) is a neurodegenerative disease that is of high importance to the
neuroscience world, yet the complex pathogenicity is not fully understood. Inflammation is …

Exposure to the herbicide paraquat (PQ) is associated with an increased risk of idiopathic
Parkinson's disease (PD). Therapies based on PQ's presumed mechanisms of action have …

Increasing data indicate that inflammation and alterations in glutamate neurotransmission
are two novel pathways to pathophysiology in mood disorders. The primary goal of this …

Alzheimer's disease (AD) currently presents one of the biggest healthcare issues in the
developed countries. There is no effective treatment capable of slowing down disease …

Astrocytes are housekeepers of the central nervous system (CNS) and are important for
CNS development, homeostasis and defence. They communicate with neurones and other …

Alzheimer's disease is the main cause of dementia in the elderly and begins with a subtle
decline in episodic memory followed by a more general decline in overall cognitive abilities …

Neuroinflammation and epilepsy are interconnected. Brain inflammation promotes neuronal
hyper-excitability and seizures, and dysregulation in the glia immune-inflammatory function …