Revitalizing Ancient Mitochondria with Nano‐Strategies: Mitochondria‐Remedying Nanodrugs Concentrate on Disease Control

X Long, M Liu, Y Nan, Q Chen, Z Xiao… - Advanced …, 2024 - Wiley Online Library
Mitochondria, widely known as the energy factories of eukaryotic cells, have a myriad of vital
functions across diverse cellular processes. Dysfunctions within mitochondria serve as …

[HTML][HTML] Potential roles of metals in the pathogenesis of pulmonary and systemic hypertension

CD Hopkins, C Wessel, O Chen… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Pulmonary and systemic hypertension (PH, SH) are characterized by vasoconstriction and
vascular remodeling resulting in increased vascular resistance and pulmonary/aortic artery …

Analyzing the molecular mechanism of xuefuzhuyu decoction in the treatment of pulmonary hypertension with network pharmacology and bioinformatics and verifying …

X Yu, W Qin, H Cai, C Ren, S Huang, X Lin… - Computers in Biology …, 2024 - Elsevier
Background XueFuZhuYu (XFZY), a typical Chinese herbal formula, has remarkable clinical
effects for treating Pulmonary Hypertension (PH) with unclear mechanisms. Our research …

[HTML][HTML] Pyroptosis, apoptosis, necroptosis and endoplasmic reticulum stress in pulmonary hypertension

Q Yan, S Liu, Y Sun, C Chen, Y Yang, S Yang… - Journal of Advanced …, 2023 - Elsevier
Background Pulmonary hypertension (PH) represents a progressive condition characterized
by the remodeling of pulmonary arteries, ultimately culminating in right heart failure and …

CeO2/Bovine Serum Albumin Nanoclusters with Robust Reactive Oxygen Species Scavenging and Improved Endothelial Dysfunction Abilities for the Treatment of …

H Zhao, Y Wu, S Fu, P Jia, Q Wang, Y Wei… - ACS Applied Nano …, 2024 - ACS Publications
Endothelial dysfunction is one of the main pathogenetic mechanisms of pulmonary
hypertension (PH). In the pathological microenvironment, excess reactive oxygen species …

Active Anchoring Stimuli‐Responsive Nano‐Craft to Relieve Pulmonary Vasoconstriction by Targeting Smooth Muscle Cell for Hypoxic Pulmonary Hypertension …

M Li, X Shang, H Lou, Z Wang, S Xiang… - Advanced …, 2024 - Wiley Online Library
Recently, nanotechnology‐based drug delivery platforms in treating pulmonary arterial
hypertension (PAH) have gradually emerged. However, large mechanical stress and shear …