Antiviral potential of garlic (Allium sativum) and its organosulfur compounds: A systematic update of pre-clinical and clinical data
Abstract Background Garlic (Allium sativum L.) is a common herb consumed worldwide as
functional food and traditional remedy for the prevention of infectious diseases since ancient …
functional food and traditional remedy for the prevention of infectious diseases since ancient …
Nuclear capsid uncoating and reverse transcription of HIV-1
TG Müller, V Zila, B Müller… - Annual review of …, 2022 - annualreviews.org
After cell entry, human immunodeficiency virus type 1 (HIV-1) replication involves reverse
transcription of the RNA genome, nuclear import of the subviral complex without nuclear …
transcription of the RNA genome, nuclear import of the subviral complex without nuclear …
Cone-shaped HIV-1 capsids are transported through intact nuclear pores
Summary Human immunodeficiency virus (HIV-1) remains a major health threat. Viral capsid
uncoating and nuclear import of the viral genome are critical for productive infection. The …
uncoating and nuclear import of the viral genome are critical for productive infection. The …
HIV-1 assembly, release and maturation
EO Freed - Nature reviews microbiology, 2015 - nature.com
Major advances have occurred in recent years in our understanding of HIV-1 assembly,
release and maturation, as work in this field has been propelled forwards by developments …
release and maturation, as work in this field has been propelled forwards by developments …
Mobile DNA in health and disease
HH Kazazian Jr, JV Moran - New England Journal of Medicine, 2017 - Mass Medical Soc
Mobile DNA in Health and Disease | New England Journal of Medicine Skip to main content
Access provided byMGH The New England Journal of Medicine homepage Advanced Search …
Access provided byMGH The New England Journal of Medicine homepage Advanced Search …
Nuclear pore blockade reveals that HIV-1 completes reverse transcription and uncoating in the nucleus
A Dharan, N Bachmann, S Talley, V Zwikelmaier… - Nature …, 2020 - nature.com
Retroviral infection involves the reverse transcription of the viral RNA genome into DNA,
which is subsequently integrated into the host cell genome. Human immunodeficiency virus …
which is subsequently integrated into the host cell genome. Human immunodeficiency virus …
Mitochondria-associated membranes (MAMs) and inflammation
The endoplasmic reticulum (ER) and mitochondria are tightly associated with very dynamic
platforms termed mitochondria-associated membranes (MAMs). MAMs provide an excellent …
platforms termed mitochondria-associated membranes (MAMs). MAMs provide an excellent …
Defective HIV-1 proviruses produce novel protein-coding RNA species in HIV-infected patients on combination antiretroviral therapy
H Imamichi, RL Dewar… - Proceedings of the …, 2016 - National Acad Sciences
Despite years of plasma HIV-RNA levels< 40 copies per milliliter during combination
antiretroviral therapy (cART), the majority of HIV-infected patients exhibit persistent …
antiretroviral therapy (cART), the majority of HIV-infected patients exhibit persistent …
HIV-1 antiretroviral drug therapy
EJ Arts, DJ Hazuda - Cold Spring Harbor …, 2012 - perspectivesinmedicine.cshlp.org
The most significant advance in the medical management of HIV-1 infection has been the
treatment of patients with antiviral drugs, which can suppress HIV-1 replication to …
treatment of patients with antiviral drugs, which can suppress HIV-1 replication to …
HIV-1 and SARS-CoV-2: Patterns in the evolution of two pandemic pathogens
Humanity is currently facing the challenge of two devastating pandemics caused by two very
different RNA viruses: HIV-1, which has been with us for decades, and SARS-CoV-2, which …
different RNA viruses: HIV-1, which has been with us for decades, and SARS-CoV-2, which …