Neuroinflammation has positive and negative effects. This review focuses on the roles of
macrophage in the PNS. Transection of PNS axons leads to degeneration and clearance of …

Acute and chronic lung injuries are among the leading causes of mortality worldwide. Lung
injury can affect several components of the respiratory system, including the airways …

Pneumonia is a type of acute lower respiratory infection that is common and severe. The
outcome of lower respiratory infection is determined by the degrees to which immunity is …

Acute respiratory distress syndrome (ARDS) is a devastating disease with distinct
pathological stages. Fundamental to ARDS is the acute onset of lung inflammation as a part …

Inflammation and tubular cell death are the hallmarks of acute kidney injury. However, the
precise mechanism underlying these effects has not been fully elucidated. Here we tested …

Background—Inflammation and activation of immune cells are key mechanisms in the
development of atherosclerosis. Previous data indicate important roles for monocytes and T …

Angiogenesis is a hallmark of malignant neoplasias, as the formation of new blood vessels
is required for tumors to acquire oxygen and nutrients essential for their continued growth …

Blood monocyte subpopulations have been defined in man initially, and the two major types
of monocytes are the CD14++ CD16− and the CD14+ CD16+ monocytes. These cells have …

The CC chemokine Monocyte Chemoattractant Protein (MCP)-1/CCL2 has potent
mononuclear cell chemo-attractant properties, modulates fibroblast and endothelial cell …

Immune-mediated pulmonary diseases are a significant public health concern. Analysis of
leukocyte behavior in the lung is essential for understanding cellular mechanisms that …