Brain tumors in children

AR Cohen - New England Journal of Medicine, 2022 - Mass Medical Soc
Brain Tumors in Children Childhood brain tumors were previously classified by histologic
appearance and location. A new classification includes genetic changes, which have …

Neuroprotective effects of quercetin in pediatric neurological diseases

L Alvarez-Arellano, M Salazar-García, JC Corona - Molecules, 2020 - mdpi.com
Oxidative stress is a crucial event underlying several pediatric neurological diseases, such
as the central nervous system (CNS) tumors, autism spectrum disorder (ASD) and attention …

Amplification of the PLAG-family genes—PLAGL1 and PLAGL2—is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification

MK Keck, M Sill, A Wittmann, P Joshi, D Stichel… - Acta …, 2023 - Springer
Pediatric central nervous system (CNS) tumors represent the most common cause of cancer-
related death in children aged 0–14 years. They differ from their adult counterparts, showing …

Essential management of pediatric brain tumors

K Lutz, ST Jünger, M Messing-Jünger - Children, 2022 - mdpi.com
Brain tumors are the most common solid tumors in children and are associated with high
mortality. The most common childhood brain tumors are grouped as low-grade gliomas …

Advances in the treatment of pediatric brain tumors

ES Kulubya, MJ Kercher, HW Phillips, R Antony… - Children, 2022 - mdpi.com
Pediatric brain tumors are the most common solid malignancies in children. Advances in the
treatment of pediatric brain tumors have come in the form of imaging, biopsy, surgical …

Pediatric neuro-oncology

F Malbari - Neurologic Clinics, 2021 - neurologic.theclinics.com
Central nervous system (CNS) tumors are the most common solid tumor in pediatrics and
represent the largest cause of childhood cancer–related mortality. 1 The incidence of CNS …

Molecular subtyping of ependymoma and prognostic impact of Ki-67

KY Lim, K Lee, Y Shim, JW Park, H Kim, J Kang… - Brain Tumor …, 2022 - Springer
Although ependymomas (EPNs) have similar histopathology, they are heterogeneous
tumors with diverse immunophenotypes, genetics, epigenetics, and different clinical …

Endothelial, pericyte and tumor cell expression in glioblastoma identifies fibroblast activation protein (FAP) as an excellent target for immunotherapy

LM Ebert, W Yu, T Gargett, J Toubia… - Clinical & …, 2020 - Wiley Online Library
Objectives Targeted immunotherapies such as chimeric antigen receptor (CAR)‐T cells are
emerging as attractive treatment options for glioblastoma, but rely on identification of a …

Neuropilin-1: a key protein to consider in the progression of pediatric brain tumors

M Douyère, P Chastagner, C Boura - Frontiers in Oncology, 2021 - frontiersin.org
Neuropilins are transmembrane glycoproteins that play important roles in cardiovascular
and neuronal development, as well as in immunological system regulations. NRP1 functions …

Atypical teratoid rhabdoid tumor: proposal of a diagnostic pathway based on clinical features and neuroimaging findings

R Calandrelli, L Massimi, F Pilato, T Verdolotti… - Diagnostics, 2023 - mdpi.com
Purpose: To assess the main imaging and clinical features in adult-and pediatric-onset
atypical teratoid rhabdoid tumor (ATRT) in order to build a predefined pathway useful for the …